background: this study investigated the association between pfcrt, t76 allele and chloroquine resistance in patients with falciparum malaria. molecular assays for point mutations on drugs resistance-related genes are applied tools for monitoring emerging resistance and surveillance malaria control strategies in endemic areas. the mutant genotype at codon 76 of plasmodium falciparum chloroquine ...

abstract background malaria is an acute and chronic illness characterized by paroxysms of fever, chills, sweating, fatigue, anemia, and splenomegaly. most malarial deaths occur in infants and young children.anemia in malaria has diverse pathophysiologic mechanisms such as direct invasion of red cells, in the following, we presented comparison of hematological aspects: children with malaria and ...

Background: Malaria is one of the most important infectious diseases in tropical and subtropical regions, 45% population living areas that suffer from stable malaria transmission Sudan. The prevalence symptomatic Plasmodium infection based on microscopy RDTs poorly documented Nyala city. This study was conducted to determine plasmodium molecular identification species city, Sudan.
 Methods...

abstract background: hypoglycaemia is a well recognized complication of falciparum malaria in children but its diagnosis may be overlooked because all the clinical features may be mimicked by severe malaria. to determine the prevalence of hypoglycaemia at the point of hospital admission of under-fives with falciparum malaria and identify its risk factors in patients seen in a nigerian secondary...

Background: Cerebral malaria (CM) is one of the major causes of death in African populations infected with Plasmodium falciparum. Only 1% of infected subjects develop CM. The reasons for these differences are not fully understood, but it is likely that the host humoral response against blood-stage antigens plays a role in protection from malaria, although the precise targets and mechanisms medi...

background: electrolytes play an important role in the normal functioning of human body. electrolyte imbalance and mineral disturbances is the common clinical manifestation in several infectious diseases including malaria. malaria is a mosquito borne serious infectious disease of the world. plasmodium vivax and p. falciparum are the main agents responsible for malaria in pakistan. electrolyte i...

abstract       background and objectives: plasmodium falciparum merozoite surface protein-1 (pfmsp-1) is a promising vaccine against malaria during its blood stages which play an important role in immunity to this disease. polymorphic nature of this gene is a major obstacle in making an effective vaccine against malaria. in this study, the genetic diversity of plasmodium falciparum isolates was...

Malaria is an infection sustained by three parasites namely: Plasmodium falciparum, Plasmodium vivax, and Plasmodium ovale. Plasmodium falciparum is the most common and virulent parasite. These parasites are present in different areas of the sub-Saharan African countries and Asia. In 2010, there were an estimated 219 million cases of malaria resulting in 660,000 deaths and, approximately, two-t...