ocular involvement is seen in approximately 25% of patients with sarcoidosis. uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. orbital manifestations of sarcoidosis are uncommon with few series in the literature. a 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. orbital scanning revealed mass in...

Background Sjogren’s syndrome (SSj) is a systemic disease with autoimmune pathogenesis, prevalent involvement of the lacrimal and salivary exocrine glands, classified as primary or secondary on basis association other rheumatic diseases. The epidemiological data in literature are variable due to heterogeneity populations examined different classification criteria used. In recent systematic revi...

Sir, Pilomatricomas are usually solitary nodules, but multiple occurrences have been observed in 2 ± 4% of cases (1, 2). The association of multiple lesions with myotonic dystrophy is well recognized (3); familial cases have also been described in association with Gardner's syndrome and sarcoidosis (4, 5). We report here the case of a girl with multiple pilomatricomas associated with sternal cl...

Etiological classification of diabetes insipidus is as follows. 1. Central Diabetes Insipidus (CDI) A. Idiopathic B. Familial C. Structural Causes i. Congenital: Septo-optic dysplasia Tuber cinereum Hamartoma ii. Traumatic: Iatrogenic, head trauma iii. Inflammatory: Tuberculous Meningitis Sarcoidosis Wegener’s granulomatosis Lymphocytic Hypophysitis iv. Neoplastic: a. Pediatric: Hypothalamic gl...

The coexistence of sarcoidosis and Crohn's disease in different members of the same family is rare and only two instances are on record. Two Indian families showing this association have been studied. In one a brother and sister are affected, and in the other seven and possibly eight persons in two generations have been affected. The familial occurrence of both these conditions supports the vie...

Between 20% and 35% of patients with systemic sarcoidosis have skin lesions. One of the unusual cutaneous presentations of sarcoidosis is a granulomatous tattoo reaction that may present alone or with other features of sarcoidosis. We present a case of sarcoidosis whom presented with multiple nodules on tattood skin accompanied with facial pulsy, parotid enlargement and uveitis.

Diffuse parenchymal lung diseases (DPLD) represent a diverse group of disorders affecting the distal lung parenchyma, specifically the tissue and spaces surrounding the alveoli, which may be filled with inflammatory cells, proliferating fibroblasts or established fibrosis, often leading to architectural distortion and impaired gas exchange. While the underlying pathogenetic mechanisms are known...

The frequency of ocular involvement ranges from 26% to 50%. The characteristics of ocular involvement are (1) when present, is seen generally early in the course of the disease (2) may co-exist with asymptomatic systemic disease and (3) can precede systemic involvement by several years. Most patients present between the ages of 20 to 40 years; however, children and the elderly can be affected. ...