نتایج جستجو برای: fibroblast like synoviocytes
تعداد نتایج: 684939 فیلتر نتایج به سال:
Rheumatoid arthritis is a chronic, destructive, autoimmune joint disease that affects one to two million Americans (or approximately 1% of the population of the United States). This disease can strike at any age and affects roughly three times as many women as men (http://ww2. arthritis.org/conditions/DiseaseCenter/RA/ra_who.asp). Symptoms include joint stiffness, swelling, and pain, as well as...
Chemokines play an essential role in the progression of rheumatoid arthritis (RA). In the present study we examined the expression and regulatory mechanisms of IFN-gamma inducible protein (IP)-10 in RA synovitis. RA synovial fluid contained greater amounts of IP-10 than did synovial fluid from patients with osteoarthritis. Immunolocalization analysis indicated that IP-10 was associated mainly w...
Iguratimod, a novel disease-modifying antirheumatic drug, which is now used in clinics in China and Japan, has been confirmed as a highly efficacious and safe drug for rheumatoid arthritis therapy. The antiarthritic mechanism of iguratimod, especially compared with that of the classical disease-modifying antirheumatic drugs, has not been elucidated. In this study, we conducted a comparative ana...
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