OBJECTIVE To determine whether a previous episode of major depression leaves a "scar" that places previously depressed patients with rheumatoid arthritis (RA) at risk for experiencing high levels of pain, fatigue, and disability. METHODS A cohort of 203 patients with RA was randomly selected from a national panel and interviewed by phone about pain, fatigue, depressive symptoms, disability, a...

People with dementia of any type have a high incidence of major depression. The occurrence of a first major depressive episode in an older adult is a risk factor for developing dementia. Management of depression in a person with dementia should be enthusiastic with an aim to optimise quality of life. Non-pharmacological and pharmacological strategies are both important in treating depression in...

OBJECTIVE We systematically review evidence on the prevalence and incidence of perinatal depression and compare these rates with those of depression in women at non-childbearing times. DATA SOURCES We searched MEDLINE, CINAHL, PsycINFO, and Sociofile for English-language articles published from 1980 through March 2004, conducted hand searches of bibliographies, and consulted with experts. M...

s | 65 PS179 A depressive patient who achieved remission by escitalopram: cerebral blood flow variation during pleasant/unpleasant image tasks. Yoshihisa Shoji, Masayuki Inoue, Youhei Ishii, Yusuke Kato, Kiichiro Morita, Naohisa Uchimira, Yuki Yamashita, Hiroko Yanagimoto Cognitive and Molecular Research Institute of Brain Diseases, Kurume

BACKGROUND Major depression is a frequent psychiatric complication among patients with traumatic brain injury (TBI). To our knowledge, however, the clinical correlates of major depression have not been extensively studied. OBJECTIVE To determine the clinical, neuropsychological, and structural neuroimaging correlates of major depression occurring after TBI. DESIGN Prospective, case-controll...

Abstract Background Antidepressant response is a complex trait influenced by clinical, demographic and genetic factors. Objectives To explore the influences of baseline depression severity, gender type depressive episode on efficacy safety escitalopram (10–20 mg/day) in South Indian patients with major disorder (MDD). Methods The study was conducted 18–65-year-old ( n = 151) suffering from firs...

Major depression is one of the most prevalent mental disorders and the number one cause of disability worldwide. Once a person experiences a major depressive episode (MDE), the likelihood of recurrence is very high. The prevention of first onset, as well as the protection against recurrence after recovery, are therefore essential goals for the mental health field. By the end of the 20th century...

Autobiographical memory in depression is characterized by an increase in general memory evocation. The aim of this study is to compare autobiographical memory in patients with a first depressive episode and in recurrent patients before and after recovery, using Williams' and Scott's autobiographical memory test. Our results show an increase of the number of general memories only with positive c...