Background and Objectives: several investigations have been done to evaluate the effect of Ramadan fasting on fetal and maternal health, which have all led to controversial results. The role of Ramadan fasting time in birth weight is still unclear. This study evaluated the effect of fasting at different periods of pregnancy on birth weight. Methods: 250 pregnant women fasting at least one day d...

background : aneuploidy is one of the main causes of congenital anomalies, mental and physical disabilities, in new-borns. the aim of this study was to determine various chromosomal aneuploidies in the first and second trimester screening of pregnant women, in iran. methods : a descriptive retrospective study was conducted on 125,170 pregnant women referred to a major referral medical diagnosti...

Background: For every pregnant woman, it is possible to have a child with chromosomal abnormalities. Although this possibility is not very high, by performing screening tests and considering the mother's background factors, we can largely realize the real extent of this possibility. Many comorbidities (like high blood pressure, diabetes, and obesity) and high-risk exposures (like alcohol consu...

background: central nervous system malformations are the second most common congenital malformations after congenital heart diseases. these malformations are associated with many instances of morbidity and mortality which underline the importance of prevention and their early diagnosis. objective: the objective of this study is the diagnosis of neural tube defect (ntds) in the first trimester a...

Background: Alkaline phosphatase (ALP), (EC 3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups from various molecules in the body. In humans, ALPis present in all tissues such as liver, bile duct, kidney, bone, and the placenta which detection of its activity is so useful in molecular biology. Pregnancy is associated with normal physiological changes that assist fetal surv...

introduction: the parikh’s formula is a calculation method that considers menstrual cycle duration in women who have an unusual interval of menstruation cycle. since the accurate estimation of gestational age affects pregnancy outcomes, the present study aimed to compare the first trimester ultrasound and parikh’s formula in determining the expected date of delivery (edd). materials and methods...

Objective: Gestational diabetes mellitus (GDM) is the most common metabolic complication during pregnancy. So, a large number of studies have evaluated the usefulness of different screening tests. The aim of this study was focused on the potential of only first-trimester screening used in the prediction of GDM. Materials and Methods: In this systematic review, we searched PubMed, EMBASE, and S...

Lesion of toxemia in first trimester pregnan­cies: Lesion of toxemia of pregnancy, compris­ing desidual arteriolar thickening, narrowing, degeneration, and endothelial vacuolization with trophoblastic degeneration and fibrin thrombi attached to degenerated chorionic villi, were evident in 46 (14.1 per cent) of 326 induced first trimester abortioruJ. No clinical features of toxemia were present,...