BACKGROUND Results of observational and experimental studies investigating the association between intake of long-chain n-3 polyunsaturated fatty acids (PUFAs) and risk of atrial fibrillation (AF) have been inconsistent. METHODS We studied the association of fish and the fish-derived n-3 PUFAs eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) with the risk of incident AF in individua...

BACKGROUND Mercury is a neurotoxin, and limited prenatal exposure to it can affect long-term child neurodevelopment. However, results of epidemiologic studies of such exposure have been inconsistent. We examined the association of prenatal mercury exposure from maternal fish consumption with child neurodevelopment in northern Italy. METHODS A population-based cohort of 606 children and their ...

BACKGROUND Fish consumption advisories are developed to prevent overexposure to various contaminants. Recently, discussion has centered on the need to consider the benefits of fish consumption alongside possible risks when providing guidance. OBJECTIVE As part of the Arsenic Mercury Intake Biometric Study involving the Japanese and Korean communities living in Washington State, we obtained fi...

BACKGROUND Associations between fish consumption and stroke risk have been inconsistent, possibly because of the differences in types of fish meals consumed. Additionally, such relationships have not been specifically evaluated in the elderly, in whom disease burden may be high and diet less influential. METHODS Among 4775 adults 65 years or older (range, 65-98 years) and free of known cerebr...

OBJECTIVE The objective of the present study was to examine the relationship of dietary fried fish consumption and risk of cardiovascular events and all-cause mortality. DESIGN Prospective cohort study among participants of the REasons for Geographic And Racial Differences in Stroke (REGARDS) study who resided in the USA. SETTING The primary outcome measures included the hazard ratios (HR) ...

The balance of contaminant risk and nutritional benefit from maternal prenatal fish consumption for child cognitive development is not known. Using data from a prospective cohort study of 341 mother-child pairs in Massachusetts enrolled in 1999-2002, the authors studied associations of maternal second-trimester fish intake and erythrocyte mercury levels with children's scores on the Peabody Pic...

OBJECTIVE To determine the relation between intake of seafood in pregnancy and risk of preterm delivery and low birth weight. DESIGN Prospective cohort study. SETTING Aarhus, Denmark. PARTICIPANTS 8729 pregnant women. MAIN OUTCOME MEASURES Preterm delivery and low birth weight. RESULTS The occurrence of preterm delivery differed significantly across four groups of seafood intake, fall...

CONTEXT Fish (finfish or shellfish) may have health benefits and also contain contaminants, resulting in confusion over the role of fish consumption in a healthy diet. EVIDENCE ACQUISITION We searched MEDLINE, governmental reports, and meta-analyses, supplemented by hand reviews of references and direct investigator contacts, to identify reports published through April 2006 evaluating (1) int...

This 1998 study investigated the association between intake of fish and fish oil during pregnancy and full-term infants' size at birth in an Icelandic fishing community. Healthy women aged 20-40 years of normal weight before pregnancy (body mass index: 19.5-25.5 kg/m(2)) and at 38-43 weeks of gestation were selected randomly. Information on infant size at birth was collected from maternity reco...

The association between fish and fish oils intake and diabetes remains largely unknown. Here we systematically reviewed published articles (clinical trials, prospective cohort studies, systematic reviews and meta-analyses) about the effects of intake of fish or fish oils on the development of diabetes. An intake of fish oils seems not to affect insulin sensitivity, insulin secretion, beta-cell ...