Hereditary diabetes insipidus is a rare endocrine disorder caused by a deficiency of the antidiuretic hormone, vasopressin. The disease is characterized by polyuria, extreme thirst, and polydipsia. In this study of six affected members from two families with hereditary diabetes insipidus, it was found that two children who drank water fluoridated at optimum levels developed moderate to severe f...

It has been suggested that systemic fluoride absorption from drinking water may be influenced by the type of fluoride compound in the water and by water hardness. Using a human double-blind cross-over trial, we conducted this study to measure c(max), T(max), and Area Under the Curve (AUC) for plasma F concentration against time, following the ingestion of naturally fluoridated hard and soft wat...

OBJECTIVE To examine some of the potential benefits and risks of water fluoridation for older adults. METHODS This study used 'The Irish Longitudinal Study on Ageing', to access a nationally representative sample of 4977 people aged 50 and older. The sample was used to estimate associations between the percentage of households in a respondent's local area with a currently fluoridated water su...

OBJECTIVE To determine the clinical effectiveness of a community milk fluoridation programme. BASIC RESEARCH DESIGN Parallel arm 5-year cohort study, with final cross-sectional comparisons between groups. PARTICIPANTS 3-year-olds in 8 Bulgarian cities/towns entered the cohort study with random samples (n = 1,782) recruited at baseline in 2004. After 5 years in 2009 sub-samples (about 30%) o...

Fluoridated mouthrinses are not advised for preschool children who may swallow much of the agent. An alternate method of delivering topical fluoride to the interproximal tooth surfaces in these young patients may be fluoridated dental floss. The purpose of this study was to determine the fluoride levels of demineralized primary enamel both before and after the use of a commercially available de...

This paper encompasses information on the status of community and school water fluoridation in the U.S. and abroad, the status and action on State fluoridation .laws, an explanation and effect of the Safe Drinking Water Act, dental benefits, and identification and refutation of the three most common areas of allegations against fluoridation. Grand Rapids that same year to demonstrate that the d...

Researchers conducted a final comparison of dental caries experience between the two communities prior to fluoridation. They sought to compare the mean dmft and dmfs indices, missing teeth, lifetime experience of dental caries and prevalence of toothache, extractions and general anesthesia for extractions between a continuously fluoridated area over the past 25 years (1976-1994) to a non-fluori...