نتایج جستجو برای: fok1
تعداد نتایج: 77 فیلتر نتایج به سال:
BACKGROUND There is considerable interest in the possible role of vitamin D in respiratory disease, but only one population-based study has reported associations with lung function. METHODS The cross-sectional relationships of total dietary vitamin D intake, serum 25 hydroxy vitamin D (25(OH)D) concentrations and three vitamin D receptor (VDR) polymorphisms (Apa1, Fok1 and Cdx2) with lung fun...
BACKGROUND Vitamin D, from diet and sunlight exposure, may be associated with reduced breast-cancer risk. This study investigated if candidate gene variants in vitamin D pathways are associated with breast cancer risk, or modify the associations between breast cancer and vitamin D exposure. METHODS Breast cancer cases aged 25 to 74 years were identified from the Ontario Cancer Registry (histo...
BACKGROUND/AIM Geographic gradients in breast cancer incidence and mortality suggest that vitamin D may reduce risk. The enzyme 25-hydroxyvitamin D 24-hydroxylase (CYP24A1), which degrades the active form of vitamin D, and the vitamin D receptor (VDR) are both found in breast tissue. We investigated six polymorphisms in CYP24A1 and two in the VDR gene in association with breast cancer risk. M...
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