101 isolates of brucella spp. including the reference (n=7) and the iranian field strains belonging to last years 1961-2003 (n=94) were biotyped and classified into 9 biotypes. random amplified polymorphic dna (rapd) analysis using a ten mer-ap4 primer was generated 72 reproduciable dna band. the typeability was 100%. the thirteen isolates were classified into five groups, each containing 2-4 b...

the genetic polymorphism of some genes related to meat production in three egyptian sheep breeds (barki, rahmani and osseimi) was studied. the candidate genes were: calpastatin, myostatin, diacylglycerol-acyltransferase1, insulin-like growth factor binding protein-3 and booroola fecundity gene. the technique applied was the restriction fragment length polymorphism for the polymerase chain react...

the families of tgf-β proteins are the most important growth factors in the ovary for growth and differentiation of early ovarian follicles. three related oocyte-derived members of the transforming growth factor-β superfamily namely growth differentiation factor 9 (gdf9), bmp15 and bmpr-ib have been shown to be essential for follicular growth and ovulation. different mutations in the gdf9 gene ...

background: pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (rm). objective: to investigate the association between rm and five polymorphisms of cytokine genes, interleukin 10 (il-10), (-592 a/c, -819 c/t, -1082 a/g), il-6 (-174 c/g) and il-17 (-197 g/a) in iranian women. method: po...

asthma as a chronic inflammatory airway disease is considered to be the most common chronic disease that is involving genetic and environmental factors. toll like receptors (tlrs) and other inflammatory mediators are important in modulation of inflammation. in this study, we evaluated the role of tlr2 arg753gln and tlr4 asp299gly polymorphisms in the asthma susceptibility, progress, control lev...

background: uterine leiomyoma (ul) is a benign tumor of uterine smooth muscle that affects women in reproductive ages. fas has an important role in initial stages of apoptosis. previous studies have shown an association between the fas gene and tumorigenesis. in the present study, we evaluated the relationship between fas a-670g (rs 1800682) and ul risk. methods: the fas gene polymorphism of 15...

background: pulmonary tuberculosis (ptb) has recently become a major problem in developed countries especially in immune compromised hiv infected individuals. cytokines, their genes and receptors have been implicated in the protective immunity, pathophysiology and development of tuberculosis.   material & methods: in the present study the genotype frequencies of a number of polymorphic genes co...

Growing consumer awareness is forcing food producers to supply raw material and products of increasingly high quality health-promoting properties. Knowledge the genetic background characteristics taking on great importance, enabling selection based molecular markers. The increasing throughput techniques, in combination with an expanding bioinformatics infrastructure, leading continual improveme...