Gene product 5 (gp5) of bacteriophage T4 is a spike-shaped protein that functions to disrupt the membrane of the target cell during phage infection. Its C-terminal domain is a long and slender β-helix that is formed by three polypeptide chains wrapped around a common symmetry axis akin to three interdigitated corkscrews. The folding and biophysical properties of such triple-stranded β-helices, ...

Mitotic chromosome structure and DNA sequence requirements for normal chromosomal condensation remain unknown. We engineered labeled chromosome regions with altered scaffold-associated region (SAR) sequence composition as a formal test of the radial loop and other chromosome models. Chinese hamster ovary cells were isolated containing high density insertions of a transgene containing lac operat...

different methods arising from scientific investigation for removing noise from chaotic signals have been introduced and one of their best is local projection approach. the local projection approach projects the chaotic data in the neighborhood onto the hyper-plane. selection of neighborhood radius has a direct impact on its performance. a noticeable feature associated with chaotic trajectories...

We present a general and mathematically rigorous algorithm which allows the helicoidal structure of a protein to be calculated starting from the atomic coordinates of its peptide backbone. This algorithm yields a unique curved axis which quantifies the folding of the backbone and a full set of helicoidal parameters describing the location of each peptide unit. The parameters obtained form a com...

This work presents a novel approach to shape matching of folded garments to unfolded templates, aiming to facilitate unfolding by robotic manipulators. The proposed method incorporates robust shape analysis techniques, estimating point correspondences between contours of folded garments and unfolded templates. The analysis results are also used for estimating the location of the folding axis on...

Recent studies in protein folding suggest that native state topology plays a dominant role in determining the folding mechanism, yet an analogous statement has not been made for RNA, most likely due to the strong coupling between the ionic environment and conformational energetics that make RNA folding more complex than protein folding. Applying a distributed computing architecture to sample ne...

Carbon fibers going through stabilization, carbonization, and graphitization heat-treatment stages will form continuous graphitic layers that are closely packed preferentially aligned along the fiber axis, forming high mechanical stiffness or strength electrical thermal conductivity. The alignment of noncontinuous, powder-like graphene in polymers has been challenging due to low bending modulus...