Spaanderman, M. E. A., M. Meertens, M. Van Bussel, T. H. A. Ekhart, and L. L. H. Peeters. Cardiac output increases independently of basal metabolic rate in early human pregnancy. Am J Physiol Heart Circ Physiol 278: H1585–H1588, 2000.—Early pregnancy is characterized by the institution of a high-flow low-resistance circulation. In this study, we tested the hypothesis that these hemodynamic chan...

Regulation of human ovarian steroidogenesis differs from other species and precise knowledge on how human small antral follicles (hSAF) develop and acquire competence for continued growth and steroid output is still incomplete. The present study has characterized almost 1,000 normal hSAF collected in connection with cryopreservation of ovarian tissue for fertility preservation. The antral folli...

In the open-pit mining, one of the first decisions that must be made in production planning stage, after completing the design of final pit limits, is determining of the processing plant cut-off grade. Since this grade has an essential effect on operations, choosing the optimum cut-off grade is of considerable importance. Different goals may be used for determining optimum cut-off grade. One of...

in order to evaluate the effects of short course administration of dexamethasone (dex) combined with clomiphene citrate (cc) in cc-resistant patients with polycystic ovary syndrome (pcas) and normal dheas, a prospective, double blind, placebo controlled, randomized study was undertaken at referral university hospitals, two-hundred and thirty women with pcos and normal dheas who failed to ovulat...

BACKGROUND To determine whether matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMP-1 and TIMP-2) in human follicular fluid, have any relationships with oocyte maturation in vivo and subsequent fertilization during in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles. METHODS The follicular fluids were obtained from 150 female patients undergoing IVF/I...

It is very difficult to differentiate follicular adenoma from follicular carcinoma in thyroid follicular lesions. The authors investigated the biological behavior of these thyroid follicular lesions using immunohistochemical techniques. Specimens taken from normal thyroid, 2 cases; follicular adenoma, 9; atypical adenoma, 7; and follicular carcinoma, 8; were observed. Proliferating cell nuclear...

The aim of this retrospective study was to investigate the impact of endogenous and exogenous luteinizing hormone (LH) activity on treatment outcome, when taking into consideration potential confounding variables. Data were derived from IVF patients (n = 358) stimulated with highly purified menotrophin (HP-hMG) in a long gonadotrophin-releasing hormone (GnRH) agonist protocol. Simple retrospect...