Patients with food hypersensitivity suffer poor quality of life and several unexplained health complaints, both abdominal and extra-abdominal. Part of the suffering is due to healthcare providers' neglect and poor insight, allowing a strong position for alternative medicine. Distinguishing food allergy from functional and organic disorders can be extremely difficult. We have found examination o...

OBJECTIVES Knowledge about the prevalence of allergies to foods in childhood and adolescence is incomplete. The purpose of this study was to investigate the prevalence of allergies to milk, egg, cod, and wheat using reported data, clinical examinations, and double-blind placebo-controlled food challenges, and to describe the phenotypes of reported food hypersensitivity in a cohort of Swedish sc...

Background: Mast cells play a central role in many infl ammatory diseases and assessment of their activation may be of use to provide objective confi rmation of the outcome of food challenge in the diagnosis of food hypersensitivity. However, to date, assessment of mastcell activation using serum markers has been unsuccessful. Objective: The aim of this study was to explore whether locally rele...

Q&A: Food additive intolerance 1) What is food additive intolerance and can you tell us what the most common symptoms are? Food additive intolerance is a non-IgE mediated food hypersensitivity. The hypersensitivity is induced by the food additives via a direct mast cell activation. Although the exact pathophysiology is unknown, various clinical signs are characteristic of food additive intolera...

BACKGROUND Abdominal complaints related to food intake might be due to hypersensitivity. A firm diagnosis of food allergy is often difficult to establish, particularly in the absence of systemic food-specific IgE. Using ultrasonography and magnetic resonance imaging (MRI) we were able to visualise the intestinal response in one such case. METHODS A 24-year-old female presented with self-repor...

Background: A clear association between allergy and nasal polyposis (NP) is not determined and the role of food intolerance in patients with NP is not investigated by oral food challenge (OFC). Objective: To investigate the relation of salicylate food intolerance and atopy in patients with NP according to recurrence and aspirin sensitivity. Methods: A cross sectional multicenter study was d...

Material and methods 238 subjects (146 women, 92 men, mean age 40,95 ±13,31 yrs with self-reported hypersensitivity reactions after fish and/or seafood ingestion were enrolled into the study. All of them were asked to answer a few questions concerning detailed medical history, clinical symptoms of food hypersensitivity and nutritional habits. Each of them underwent skin prick tests with twelve ...

BACKGROUND Patients with unexplained self-reported food hypersensitivity and irritable bowel syndrome (IBS) suffer from several health complaints, including fatigue. The aim of the present study was to validate a Norwegian translation of the Fatigue Impact Scale (FIS), and to assess the impact of fatigue in patients with self-reported food hypersensitivity and IBS, as compared with healthy cont...

Background In general, different foods and food ingredients are believed to be causing hypersensitivity/allergy among the Sri Lankan population. Global epidemiological observations have revealed lists and levels of hypersensitive foods but proper researches have been carried out in Sri Lanka for identifying food allergens. This study was carried out to obtain statistical data for different food...