INTRODUCTION There is currently no cure for the skeletal dysplasia osteogenesis imperfecta (OI), a debilitating disease that occurs in approximately 1 in every 20,000 human births. OI is caused by a genetic mutation that results in brittle bones and many fractures. In a mouse model of the disease, oim, we have characterized bone structure using X-ray microtomography, and found that oim bone has...

Intrathoracic displacement of the humeral head is a very uncommon condition and can be life threatening due to lungor heart injuries. There is a report of this condition where intrathoracic bone fragment was missed. Because of rareincidence there is no guideline for approach and treatment of this condition.We hereby present a case of intrathoracic displacement of fractured hum...

BACKGROUND Within traumatology a common indication for acute surgery of fractured clavicles is bone shortening over 2 cm. This indication is among but a few indications; which are recommended to be treated operatively within the very first weeks after a fracture. Theoretically clavicle fractures could become less shortened over time due to decreasing muscle pull. If this reduced shortening does...

cantilever bone graft, nasal reconstruction, saddle nasal deformity. Abstract The concept of the cantilever bone graft, popularised by Millard (1966), and its subsequent modification by Chait et al. (1980), led to the idea of the costochondral cantilever graft for nasal dorsum augmentation. Over 150 costochondral nasal grafts have been performed at the Australian Craniofacial Unit (ACFU) over t...

OBJECTIVE To determine the etiology and pattern of maxillofacial injuries in the Armed Forces of Pakistan in terms of anatomical distribution of injuries. DESIGN A descriptive study. PLACE AND DURATION OF STUDY January 2001 to Jan 2004 at the Oral and Maxillofacial Surgery Department, AFID, Rawalpindi. PATIENTS AND METHODS Three hundred consecutive patients of Armed Forces of Pakistan wit...

The ideal temporary implant should offer enough mechanical support to allow healing of the fracture and then biodegrade and be resorbed by metabolic mechanisms without causing any toxic effect. The aim of this research has been to simultaneously study in situ bone healing and the biodegradation of AZ31 Mg alloy as an osteosynthesis material. The in vivo study was carried out in AZ31 implants wi...

Bone has a capability to repair itself when it is fractured. Repair involves the generation of intermediatetissues, such as fibrous connective tissue, cartilage and woven bone, before final bone healing can occur. Theprocess of cartilage-to-bone transition (CBT) is a key for the achievement of rigid bone healing duringfracture repair. We tested this potential for elastic cartilage using a long ...

INTRODUCTION Currently, Vitamin D deficiency is a major public health problem and it affects more than one billion people worldwide. Vitamin D is crucial for bone mineralization and ossification. Patients with fractures need Vitamin D for the healing of their fractured bone. The current study was carried out to determine if there is change in the serum level of Vitamin-D associated with factors...

Mechanical stimulation affects the evolution of healthy and fractured bone. However, the effect of applying cyclical mechanical stimuli on bone healing has not yet been fully clarified. The aim of the present study was to determine the influence of a high-frequency and low-magnitude cyclical displacement of the fractured fragments on the bone-healing process. This subject is studied experimenta...

the femur, grazing and shattering the bone, but not injuring the popliteal vessels or the hamstring tendons. Crepitus could be distinctly felt on movement of the limb, and fractured bone was felt with.the probe. The escape of synovial fluid in large quantities a few days later, showed that the fracture extended into the knee-joint, but there was no displacement of the bone or distortion of the ...