Osteoporosis & bone fragility Every second woman and every fifth man aged 50 years or over sustains a fragility fracture (vertebral, hip, wrist or proximal humerus facture) during the rest of their lifetime [1]. Fractures virtually always lead to temporary morbidity, and with age, the likelihood of permanent and more severe comorbidities markedly increases [2]. For example, of those who sustain...

Fragility fractures, including neck of femur fractures, result from reductions in the amount, quality and architecture of bone. The aim of this study was to compare the cancellous bone structure, and static indices of bone turnover, in female patients who had sustained fragility fracture at the femoral neck, with age-matched females without fragility fracture. Bone samples were taken from the i...

OBJECTIVE Analysis of clinical documents such as bone mineral density (BMD) reports is an important component of program evaluation because it can provide insights into the accuracy of assessment of fracture risk communicated to patients and practitioners. Our objective was to compare fracture risk calculations from BMD test reports to those based on the 2010 Canadian guidelines. METHODS We r...

British Journal of General Practice, December 2012 667 INTRODUCTION Fragility fractures result from mechanical forces that would not ordinarily result in fracture. The World Health Organization (WHO) has quantified this as forces equivalent to a fall from a standing height or less. Reduced bone density is a major risk factor for fragility fractures. The prevalence of osteoporosis increases mark...

Background Calcium and Vitamin D supplementation in elderly patients may decrease the risk of hip fracture by up to one-third. Many patients suffering fragility fractures do not go on to receive this treatment despite clear recommendations from the National Institute for Health and Clinical Excellence (NICE). The aim of this study was to audit the proportion of patients admitted with a hip frac...

Fractures are the main problems related to bone fragility in postmenopausal women and account for the increase in the risk of new fractures, mortality, and costs. This study's objective was to verify the occurrence of vertebral fragility fracture and correlate it with demographic, behavioral, and clinical factors in a Brazilian population. The cross-sectional study was based on a random sample ...

A key finding of our study is that children with type 1 diabetes were at increased risk of fracture compared with age-, sex-, and practice-matched participants without diabetes (1). In his commentary (2), Dr. Shah questions the clinical significance of childhood fractures and the contribution of type 1 diabetes to fracture risk in children. To clarify, in participants with type 1 diabetes and p...

Osteogenesis imperfecta (O.I.) is a genetic disorder with increased bone fragility and low bone mass. We report the history of a 17-year-old male patient with O.I. who presented a fracture of his left femoral shaft. He had osteogenesis imperfecta type I A according to Silence. He had presented two years previously an ipsilateral cervical fracture of the femur which had healed. Intramedullary fi...

OBJECTIVE Sarcopenia might be associated with bone fragility in elderly individuals. This study aimed to investigate the prevalence of sarcopenia and its association with fragility fracture sites in elderly Chinese patients. METHODS Patients (322 men and 435 women) aged 65-94 years and with a history of fragility fractures in the ankle, wrist, vertebrae or hip, and healthy men (n = 1263) and ...