PURPOSE LINGO-1 is a functional member of the Nogo66 receptor (NgR1)/p75 and NgR1/TROY signaling complexes that prevent axonal regeneration through RhoA in the central nervous system. LINGO-1 also promotes cell death after neuronal injury and spinal cord injury. The authors sought to examine whether blocking LINGO-1 function with LINGO-1 antagonists promotes retinal ganglion cell (RGC) survival...

This article starts with the analysis of contact between laser processing bionic brake drum unit body and pad performs force based on elastic mechanics mechanics. By using Preston equation, wear caused by is obtained, as well relevant factors influence rule which affects are found. During body, in order to reduce pad, height should be minimized. Besides, light intensity at centre spot reduced, ...

During the braking action, the kinetic energy produced at the wheel is transformed into heat energy, which doesn’t dissipate fast enough into the air stream from the brake to the brake disk; as a result, the thermal conductivity plays a critical role in handling such heat generated. Thermal judder, which is a result of non-uniform contact cycles between the pad and the disk brake rotor, which i...

The connection of two phenomena, nonconservative friction forces and dissipation-induced instability, can lead to many interesting engineering problems. We study the general material-dependent damping influence on dynamic instability disc brake systems leading squeal. effect is demonstrated minimal complex models a brake. Experimental analyses through frequency response function (FRF) show diff...

The electronic wedge brake system (EWB) used in the automotive industry is a new structure designed for brake-by-wire systems. This paper proposes novel EWB which mainly composed of screw-driven wedged inner pad, fixed outer caliper-flexible rotor and hybrid stepper motor. proposed does not have planetary gear set or ball screw mechanism, it simplified existing to take advantage self-interlocki...

In this research, field and laboratory testing of three commercially available brake pads with the lowest, mid-dle, highest price were performed. Complex testing, where tested in real extreme conditions on a loaded van vehicle tests The intended to investigate temperatures that occur during braking process determine stopping distance, deceleration, time separately type pads. Labo-ratory include...