Two new cevanine steroidal alkaloids, impericine (1) and forticine (2) along with known bases delavine (3), persicanidine A (4), and imperialine (5) were isolated from the bulbs of Fritillaria imperialis. The structures of impericine (1) [(20R,22S,25S)-5alpha-cevanin-23-ene-3beta,6beta,16beta-triol] and forticine (2) [(20S,22S,25S)-5alpha-cevanine-3beta,6beta-diol] were determined with the help...

BACKGROUND Traditional Chinese medicine (TCM) herbal formulae provide valuable therapeutic strategies. However, the active ingredients and mechanisms of action remain unclear for most of these formulae. Therefore, the identification of complex mechanisms is a major challenge in TCM research. METHODS This study used a network pharmacology approach to clarify the anti-inflammatory and cough sup...

BACKGROUND The scarce fritillary Euphydryas (Hypodryas) maturna (L.) is included in the Habitats Directive's Annexes II and IV(a). Therefore, it is crucially important to be able to define the habitat and breeding places of E.maturna in a correct and unbiased way. NEW INFORMATION Data on a previously unknown pre-diapause main host plant, the small cow-wheat (Melampyrumsylvaticum L.), of Euphy...

The regal fritillary ("regal") (Speyeria idalia) is endangered in Wisconsin, USA, and declining and at risk range-wide. During 1988-2015, we surveyed 24 known regal sites and >100 areas of potential habitat in Wisconsin. We recorded 9037 individuals in 742.7 km on the peak survey per year at occupied sites. At six sites surveyed over 5-25 years, we found regal fritillaries in only one year, mos...

Feulgen bands can be obtained at the sites of constitutive heterochromatin in the chromosomes of Anemone blanda, Fritillaria lanceolata and Scilla siberica, simply by means of a short or extended acid hydrolysis. Extended hydrolysis gives positive bands in A. blanda and F. lanceolata and negative bands in S. siberica. Short hydrolysis gives no bands in A. blanda and S. siberica but gives negati...

Regal Fritillary (Speyeria idalia) primarily inhabits prairie, a native grassland of central North America, and occurs rarely in nonprairie grasslands further east. This butterfly has experienced widespread decline and marked range contraction. We analyze Regal Fritillary incidence and abundance during 1977-2014 in 4th of July Butterfly Counts, an annual census of butterflies in North America. ...

Fritillaria is a perennial herb with medicinal properties. There are 158 species worldwide, 33 of which have reported therapeutic efficacy. Alkaloids the principal constituents in Fritillaria. growing at 2700–4000 m sources extract namely Chuan Beimu (the Pharmacopoeia People’s Republic China, 2020 Edition), low biomass, mainly containing more 5?-cevanine isosteroidal alkaloids cis-configuratio...