Background According to the dementia progression, especially in Alzheimer’s disease (AD), venous reflex disturbance may be concerned. We previously found and reported that validation of spontaneous echo contrast or velocities internal jugular vein are convenient AD diagnosis screening methods reflux correlates with development (Matsuzono K et al. J Alzheimers Dis. 2021;84(2):787-796). In order ...

OBJECTIVES: Reversible causes are thought to explain about eight percent of all dementias. Hypothyroidism is one the most important potentially reversible dementia. Deficits in memory, psychomotor slowing, general intelligence, and visuoperceptual skills particularly involved may not fully recover. We review a clinical case dementia caused by hypothyroidism, patientfollowed our institution. MET...

The Frontal Assessment Battery is a set of six subtests that is used widely to assess frontal cortical executive dysfunction. Performance on the Frontal Assessment Battery has been shown to be sensitive to various neurodegenerative diseases, but it has never been shown to be sensitive to damage restricted to the frontal cortex. Thus, despite its wide use, it has never been validated on an appro...

The Frontal Assessment Battery is a set of six subtests that is used widely to assess frontal cortical executive dysfunction. Performance on the Frontal Assessment Battery has been shown to be sensitive to various neurodegenerative diseases, but it has never been shown to be sensitive to damage restricted to the frontal cortex. Thus, despite its wide use, it has never been validated on an appro...

The surgical procedure used to treat an unruptured intracranial aneurysm (UIA) has controversial effects on cognitive function. From January 2010 through December 2012, we enrolled patients who underwent surgical clipping for a UIA. Patients were tested within one week prior to surgery and again postoperatively (6.8 ± 2.3 days) using a neuropsychological battery comprising the Mini-Mental State...

The objectives of this study were to detect age-related differences in activation of the prefrontal cortex (PFC) during the tasks of hand motions and to determine an activity-related task type activating the PFC. PFC activation during three tasks, three subtests of the Frontal Assessment Battery (FAB), was investigated in 77 healthy adults by using near-infrared spectroscopy (NIRS). The tasks w...

BACKGROUND This study aimed to evaluate synthetic cannabinoid (SC)-induced psychosis in terms of patient profile and clinical characteristics with reference to concurrently hospitalized schizophrenic patients. METHODS A total of 81 male patients diagnosed with psychotic disorder induced by the use of SCs (n=50; mean (standard deviation [SD]) age: 25.9 (5.5) years) or with schizophrenia (n=31,...

Background: Neuropsychiatric symptoms in patients with frontotemporal dementia (FTD) are highly prevalent and may complicate clinical managements. Objective: We tested whether the Neuropsychiatry Inventory (NPI) could detect change neuropsychiatric caregiver´s distress diagnosed behavioral variant (bvFTD) Alzheimer’s disease (AD) from baseline to a 12-month follow-up. Methods: The sample consis...