نتایج جستجو برای: fsl

تعداد نتایج: 738  

2005
RAFAEL V. RIBEIRO GUSTAVO M. SOUZA RICARDO F. OLIVEIRA EDUARDO C. MACHADO

(Photosynthetic responses of tropical tree species from different successional groups under contrasting irradiance conditions). This study evaluated the photosynthetic responses of seven tropical trees of different successional groups under contrasting irradiance conditions, taking into account changes in gas exchange and chlorophyll a fluorescence. Although early successional species have show...

Journal: :Journal of visualized experiments : JoVE 2011
Deborah A Blake Nicolai V Bovin Dan Bess Stephen M Henry

The ability to modify/visualize biological surfaces, and then study the modified cell/virion in a range of in vitro and in vivo environments is essential to gaining further insight into the function of specific molecules or the entire entity. Studies of biological surface modification are generally limited to genetic engineering of the organism or the covalent attachment of chemical moieties to...

2016
Eleanor Williams Katie Barr Elena Korchagina Alexander Tuzikov Stephen Henry Nicolai Bovin Patricia Berninsone

The ability to glycosylate surfaces has medical and diagnostic applications, but there is no technology currently recognized as being able to coat any surface without the need for prior chemical modification of the surface. Recently, a family of constructs called function-spacer-lipids (FSL) has been used to glycosylate cells. Because it is known that lipid-based material can adsorb onto surfac...

2017
Surinder S. Rana Vishal Sharma Ravi Sharma Radhika Srinivasan Rajesh Gupta

BACKGROUND Fine-needle aspiration (FNA) of focal splenic lesions (FSL) is usually done under ultrasound (US) or computed tomography guidance. Endoscopic US (EUS), because of its ability to provide high-resolution images, can be used for aspirating FSL. We studied the safety and efficacy of EUS-guided FNA of FSL. METHODS We performed a retrospective analysis of patients with FSL undergoing EUS...

Journal: :Behavioural brain research 2006
Y Braw O Malkesman M Dagan A Bercovich Y Lavi-Avnon M Schroeder D H Overstreet A Weller

Animal models have been used in understanding the neuro-biological basis of depression and predicting successful treatment strategies. The current study focused on two genetic models of depression, the Flinder's Sensitive Line (FSL) and Wister-Kyoto (WKY). Our laboratory showed depressive symptomatology in pre-pubertal WKY and FSL rats, and the current study focused on the strains' anxiety-like...

Journal: :Behavioural brain research 2005
O Malkesman Y Braw O Zagoory-Sharon O Golan Y Lavi-Avnon M Schroeder D H Overstreet G Yadid A Weller

One of the most important criteria for major depressive disorder in adults and in children and adolescents as well, is the loss of interest in or pleasure from typically enjoyable experiences or activities: anhedonia. Anxiety is frequently co-morbid with depression. We examined reward and anxiety in genetic animal models of childhood depression. Two different "depressed" lines were studied: the...

Journal: :Psychosomatic medicine 2002
Elliot M Friedman Kelly A Becker David H Overstreet David A Lawrence

OBJECTIVE Clinical depression is associated with multiple abnormalities of immune function, including reduced virus-specific responses. This study tested the hypothesis that the Flinders Sensitive Line (FSL) rat, a promising genetic animal model of depression, would exhibit reductions in antigen-specific primary antibody responses to immunization. METHODS FSL (N = 13) and control Flinders Res...

Journal: :Transactions of the Association for Computational Linguistics 2021

We explore few-shot learning (FSL) for relation classification (RC). Focusing on the realistic scenario of FSL, in which a test instance might not belong to any target categories (none-of-the-above, [NOTA]), we first revisit recent popular dataset structure pointing out its unrealistic data distribution. To remedy this, propose novel methodology deriving more from available datasets supervised ...

2007
Cara M Hildreth James R Padley Paul M Pilowsky Ann K Goodchild

Serotonin (5HT) is crucial to normal reflex vagal modulation of heart rate (HR). Reduced baroreflex sensitivity (sBRS) and HR variability (HRV) reflect impaired neural, particularly vagal, control of HR and are independently associated with depression. In conscious, telemetered Flinders-Sensitive Line rats (FSL), a well-validated animal model of depression, we tested the hypothesis that cardiov...

Journal: :The international journal of neuropsychopharmacology 2010
Betina Elfving Pia Høgh Plougmann Heidi Kaastrup Müller Aleksander A Mathé Raben Rosenberg Gregers Wegener

There is accumulating evidence that brain-derived neurotrophic factor (BDNF) plays a critical role in the pathophysiology of depression. Decreased serum levels have been reported in major depression, and a correlation between BDNF reduction and the severity of the disease was found. Moreover, in post-mortem hippocampal tissue, increased levels of BDNF immunoreactivity have been reported in subj...

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