نتایج جستجو برای: ftc

تعداد نتایج: 1578  

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده مهندسی کامپیوتر 1391

ناحیه بندی یک گام ابتدایی و بسیار مهم در مباحث تحلیل تصویر است که نقش اساسی در تشخیص، طرح ریزی جراحی، و ارزیابی های مختلف پزشکی ایفا می کند. ناحیه بندی تصاویر پزشکی به دلیل ناهمگونی بافت، اثر حجم جزئی، نویز، آرتیفکت و تنوع ساختار بیماری های مختلف در بیماران گوناگون با مشکل مواجه است. برای حل مشکلات مذکور روش مدل های دگرشکل پذیر سطح پیشنهاد شده است. هدف از این رساله بررسی مدل های دگرشکل پذیر برا...

Journal: :Journal of molecular endocrinology 2009
Bogusz Trojanowicz Anja Winkler Kathrin Hammje Zhouxun Chen Carsten Sekulla Dagobert Glanz Cornelia Schmutzler Birgit Mentrup Sabine Hombach-Klonisch Thomas Klonisch Rainer Finke Josef Köhrle Henning Dralle Cuong Hoang-Vu

Retinoic acid (RA) acts as an anti-proliferative and redifferentiation agent in the therapy of thyroid carcinoma. Our previous studies demonstrated that pretreatment of follicular thyroid carcinoma cell lines FTC-133 and FTC-238 resulted in decreased in vitro proliferation rates and reduced tumor cell growth of xenotransplants. In addition to the previous results, we found that RA led to decrea...

2016
Seung-Hyun Jung Min Sung Kim Chan Kwon Jung Hyun-Chun Park So Youn Kim Jieying Liu Ja-Seong Bae Sung Hak Lee Tae-Min Kim Sug Hyung Lee Yeun-Jun Chung

Follicular thyroid adenoma (FTA) precedes follicular thyroid carcinoma (FTC) by definition with a favorable prognosis compared to FTC. However, the genetic mechanism of FTA to FTC progression remains unknown. For this, it is required to disclose FTA and FTC genomes in mutational and evolutionary perspectives. We performed whole-exome sequencing and copy number profiling of 14 FTAs and 13 FTCs, ...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2014
Michelle L James Bin Shen Carsten H Nielsen Deepak Behera Christine L Buckmaster Christophe Mesangeau Cristina Zavaleta Pradeep K Vuppala Seshulatha Jamalapuram Bonnie A Avery David M Lyons Christopher R McCurdy Sandip Biswal Sanjiv S Gambhir Frederick T Chin

UNLABELLED The noninvasive imaging of σ-1 receptors (S1Rs) could provide insight into their role in different diseases and lead to novel diagnostic/treatment strategies. The main objective of this study was to assess the S1R radiotracer (18)F-FTC-146 in rats. Preliminary squirrel monkey imaging and human serum/liver microsome studies were performed to gain information about the potential of (18...

Journal: :Antimicrobial agents and chemotherapy 2011
Déborah Hirt Alain Pruvost Didier K Ekouévi Saïk Urien Elise Arrivé Mamourou Kone Eric Nerrienet Mandisa Nyati Glenda Gray Leang Sim Kruy Stéphane Blanche François Dabis Jean-Marc Tréluyer

Our objective was to investigate neonatal emtricitabine (FTC) plasma and intracellular pharmacokinetics. The study was designed as a phase I/II prospective trial in two sequential steps evaluating the combination of tenofovir disoproxil fumarate (TDF) and FTC for the prevention of mother-to-child-transmission (PMTCT) of HIV. HIV-1-infected pregnant women received two tablets of TDF (300 mg) and...

Journal: :Journal of acquired immune deficiency syndromes 2013
Jessica L Adams Craig Sykes Prema Menezes Heather M A Prince Kristine B Patterson Katrien Fransen Tania Crucitti Irith De Baetselier Lut Van Damme Angela D M Kashuba

BACKGROUND The active metabolites of tenofovir (TFV) and emtricitabine (FTC) in peripheral blood mononuclear cells (PBMCs) have been used as markers of long-term antiretroviral (ARV) adherence. However, the process of isolating PBMCs is expensive, complex, and not feasible in many settings. We compared concentrations of TFV-diphosphate (TFV-DP) and FTC-triphosphate (FTC-TP) in the upper layer p...

2014
Teri Liegler Mohamed Abdel-Mohsen L. Gordon Bentley Robert Atchison Timothy Schmidt Jacqueline Javier Megha Mehrotra Christopher Eden David V. Glidden Vanessa McMahan Peter L. Anderson Peilin Li Joseph K. Wong Susan Buchbinder Juan V. Guanira Robert M. Grant

BACKGROUND The iPrEx study demonstrated that combination oral emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) as preexposure prophylaxis (PrEP) protects against HIV acquisition in men who have sex with men and transgender women. Selection for drug resistance could offset PrEP benefits. METHODS Phenotypic and genotypic clinical resistance assays characterized major drug resistant mut...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2012
Maseeh uz Zaman Nosheen Fatima Zafar Sajjad Jaweed Akhtar Najmul Islam Qamar Masood Asma Ahmed

BACKGROUND In papillary and follicular thyroid cancers (PTC, FTC), nodal and distant metastasis are generally considered important determinants of recurrence and survival, respectively. However, there is no consensus about the threshold primary tumour size (PTS) for these determinants. The aim of this study was to assess size relationships for developing nodal, pulmonary, bone and overall dista...

Journal: :International journal of clinical and experimental pathology 2015
Le Zhao Xiao-Yun Zhu Rong Jiang Man Xu Ni Wang George G Chen Zhi-Min Liu

It is extremely difficult to discriminate between follicular thyroid carcinoma (FTC) and follicular thyroid adenoma (FTA) before surgery, because the morphologies of carcinoma cells and adenoma cells obtained by fine needle aspiration biopsy (FNAB) are similar. Molecular markers may be helpful on this issue. The purpose of this study was to assess the role of GPER1, EGFR and CXCR1 in differenti...

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