The Drosophila Frizzled (Fz) and Frizzled2 (DFz2) proteins function as receptors for Wingless (Wg) in tissue culture cells. While previous results indicate that loss of function for fz has tissue polarity defects, loss-of-function effects of Dfz2 are not known. Here, we have examined the requirements of fz and Dfz2 during neurogenesis. Our results indicate that both Fz and DFz2 function in Wg s...

Frizzled (Fz) proteins are serpentine receptors that transduce critical cellular signals during development. Serpentine receptors usually signal to downstream effectors through an associated trimeric G protein complex. However, clear evidence for the role of trimeric G protein complexes for the Fz family of receptors has hitherto been lacking. Here, we show roles for the Galpha(o) subunit (Go) ...

We evaluated the impact of outdoor exercise equipment (FZ, Fitness Zones) in 12 parks serving diverse populations. We used the System for Observing Play and Recreation in Communities (SOPARC) to assess use and estimate energy expenditure prior to and twice after FZ installation. Park use increased more in FZ parks than in 10 control parks that did not get equipment, but the difference was not s...

The tissue polarity genes in Drosophila are required to coordinate cell polarity within the plane of the epidermis. Evidence to date suggests that these genes may encode components of a novel signal transduction pathway. Three of the genes, frizzled (fz), dishevelled (dsh), and prickle (pk) share a similar tissue polarity phenotype, suggesting that they function together in a single process. ds...

Hideki Kobayashi 1, Rene Halver 2, Godehard Sutmann 2 and Roland G. Winkler 1,* 1 Theoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, D-52425 Jülich, Germany; [email protected] 2 Jülich Supercomputing Centre, Institute for Advanced Simulation, Forschungszentrum Jülich, 52425 Jülich, Germany; r.halver@fz...

The long-term success of a composite restoration largely depends on its smoothness, which can be achieved by the appropriate polishing tools and material selection. purpose this study was to evaluate surface roughness two materials after application selected systems. Filtek Ultimate (FU) Z250 (FZ) were tested. Forty specimens each prepared. After polymerization under Mylar strip, five samples f...

BACKGROUND The small GTPases Rac and Rho act as cellular switches in many important biological processes. In the fruit fly Drosophila, RhoA participates in the establishment of planar polarity, a process mediated by the receptor Frizzled (Fz). Thus far, analysis of Rac in this process has not been possible because of the absence of mutant Rac alleles. Here, we have investigated the role of Rac ...

Abstract In this paper, the effect of autogenous diode laser beam welding (LBW) and influence post weld heat treatment (PWHT) on microstructural changes mechanical properties dual phase DP1400 high strength steel (HSS) butt welded joint are studied presented. LBW PWHT were performed 1 mm sheet thickness using 3 5 kW systems, respectively. The technology ensures quality joints in HSS facilitate ...

The floating zone (FZ) method is one of the growth techniques used to grow single crystal materials. FZ growth is achieved in a containerless environment (without a crucible) by the movement of a molten zone of a solid rod, which forms a free-standing liquid bridge between two solid sections. However, the surface tension along the free surface of the molten zone varies due to temperature and co...

The floating zone (FZ) method is one of the growth techniques used to grow single crystal materials. FZ growth is achieved in a containerless environment (without a crucible) by the movement of a molten zone of a solid rod, which forms a free-standing liquid bridge between two solid sections. However, the surface tension along the free surface of the molten zone varies due to temperature and co...