The work describes purification and biochemical characterization of two inducible antimicrobial peptides from the hemolymph of Galleria mellonella. The peptides were isolated by a sequence of reversed-phase chromatography steps from the hemolymph of larvae immunized with viable bacteria. The first peptide is a member of the cecropin family while the second one is rich in proline residues and ha...

Nonmammalian model systems of infection such as Galleria mellonella (caterpillars of the greater wax moth) have significant logistical and ethical advantages over mammalian models. In this study, we utilize G. mellonella caterpillars to study host-pathogen interactions with the gram-negative organism Acinetobacter baumannii and determine the utility of this infection model to study antibacteria...

the development times and the survival rates of different stages of habrobracon hebetor say reared on the last instar larvae of galleria mellonella (l.) were compared at ten different constant temperatures (16 - 38 âºc). the development time of immature stages of the parasitoid, h. hebetor, decreased as the temperature increased in the range of 16 to 38 âºc. however, no larvae could survive and...

The gastrointestinal tract in both mammals and insects is associated with microbes (collectively the microbiota), which are controlled by the intestinal immune system. These microbes regulate pathogens that can infect gut epithelial cells, and there is increasing evidence for a reciprocal relationship between beneficial and pathogenic bacteria in the gut and the intestinal immune system. Deciph...

Bioassays were carried out in the laboratory to determine the virulence of two Beauveria bassiana indigenous isolates on the greater wax moth Galleria mellonella. LC50 and LT50 values were taken as indices for the efficacy of fungal isolates, designated as Bb1 and Bb2, collected from Ismailia governorate in Egypt and isolated from soil and trap larvae of G. mellonella, respectively. The larvae ...

Candida auris, first described in 2009, has since emerged as an important, multidrug-resistant, nosocomial agent of candidemia, with large outbreaks reported worldwide and high mortality rates associated with therapeutic failure. The current study employed C. auris isolates from a variety of centers in the United Kingdom to evaluate the pathogenicity of this emerging pathogen compared to that o...

In this study, wax worm larvae (Galleria mellonella) were used to examine their ability degrade and assimilate polyethylene (PE) as an energy source. This idea came from the similarity of wax, that is sole diet for larvae, with PE in composition. Morphology changes, weight loss, FTIR analysis GC-Mass test studied prove degradation by G. mellonella. The maximum depth holes on plastic surface 16%...