Introduction THERE has been recent interest in the ophthalmological and general medical literature on the prophylactic treatment of tetanus. However, tetanus is only one disease caused by the spore-forming, Gram-positive, obligate, anaerobic rods known as the Clostridia. In addition to tetanus this group of pathogens also causes gas gangrene and botulism. The most common offenders of this speci...

Gas gangrene is a rare but often fatal soft-tissue infection. Because it is uncommon and the classic symptom of crepitus does not appear until the infection is advanced, prompt diagnosis requires a high index of suspicion. We present a case report of a middle-aged man who presented with acute onset lower-extremity pain that was initially thought to be due to deep vein thrombosis. After undergoi...

In an earlier paper, Reed, Orr and Smith (1941), demonstrated that the more actively pathogenic species of gas-gangrene anaerobes produce fibrinolysis when tested by the familiar procedure of Tillet and Garner (1933). Carlsen (1939) has previously shown that Clostridium histolyticum produces an active fibrinolysin. The eleven species of the genus Clostridium (some seventy-seven strains) tested ...

INTRODUCTION Liver gas gangrene is a rare condition with a highly mortality rate. It is mostly associated with host factors, such as malignancy and immunosuppression. PRESENTATION OF CASE A 57-year-old female was admitted to our hospital with abnormalities of her serum hepato-biliary enzymes. She had a history of hypertension, diabetes mellitus, cerebral infarction, and chronic renal failure....

TO THE EDITOR—Several of us have served in the military, and the recent cover of Clinical Infectious Diseases (The Treatment of a Gangrenous Leg, woodcut, 16th century) [1] intrigued us. We wondered how much aggressive surgical debridement and effective antibiotic regimens have improved survival of patients with gas gangrene since that time? Clostridialmyonecrosis (gas gangrene), a monomicrobia...

BACKGROUND Fourniers gangrene caused by synergic aerobic and anaerobic organism is a life threatening disorder. METHODS The medical records of 8 among 839 patients admitted to imam ali general hospital Zahedan university of Medical Sciences with fourniers gangrene during the 10 months period between 2012 and 2013 were reviewed. RESULTS The most common etiology and presentation were abscess ...

was good. The wound was cleaned with antiseptic lotions and ether, and the edges which were widely apart were stitched together. Anti-tetanic serum, 1,500 international units, was injected. He was put on an alkaline mixture and sulphonamide tablets (septanilam 0.5 gramme) 6 a day divided in 3 doses. An injection of morphia grain 1/6 with atropine grain 1/200 was also given to relieve the pain. ...

Mucormycosis is a disease caused by a fungus from the Phycomycetes class and the Mucorales order. Phycomycetes are ubiquitous fungi occurring in soil, air, skin, body orifices, manure, and food. They are commonly seen in diabetics, particularly in patients with ketoacidosis.'" Numerous other predisposing conditions have been reported.2 36 Gas gangrene refers to a necrotising infection of the so...