The sequence of events in the gastric mucosa that precede the manifestation of gastric cancer has been shown to begin decades earlier. Typically, it begins with chronic non-atrophic gastritis that progresses to chronic atrophic gastritis, which may eventually lead to intestinal metaplasia, dysplasia, and finally adenocarcinoma (Kuipers, 1999). Helicobacter pylori infection is accepted as the pr...

Chronic gastritis and gastric atrophy are common in later adult life. Hebbel (1943) investigated the incidence of chronic gastritis at necropsy in patients dying from a variety of causes but whose history revealed no evidence of gastric symptoms. He found that gastric changes of any degree were rare below the age of 30 years and severe changes uncommon below the age of 50 years. Atrophic gastri...

Background: This study was designed to determine if it is important to add corpus biopsies to the routine antral ones for identification of H. pylori, especially in case of gastric atrophy and/or intestinalmetaplasia. Methods: This is a prospective multicenter study including three hundred and twenty eight patients with gastritis from June 2014 through Dec.2015. Endoscopic mucosal biopsies from...

Helicobacter pylori affects gastric acid secretion via several mechanisms. One of these is by changing gastric regulatory physiology. The infection elevates plasma gastrin levels and decreases gastric mucosal expression of the inhibitory peptide somatostatin. These changes may be due to products of H. pylori itself or inflammatory cytokines released in H. pylori infection: acid secretion is inh...

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In 2013, the Japan Gastroenterological Endoscopy Society introduced Kyoto classification of gastritis, which is useful to predict Helicobacter pylori infection based exclusively on endoscopic findings. Based gastric mucosal atrophy, intestinal metaplasia, hypertrophic folds, nodularity, and diffuse redness may be associated with cancer H. infection, are common findings in Koreans. Atrophy metap...

Gastric anisakiasis is a parasitic disease caused by the consumption of seafood infested with third-stage larvae of the nematode Anisakis simplex or related species. Patients typically present with acute and severe abdominal pain, nausea, and vomiting. Endoscopic removal is the standard therapy. With the increase in incidence of gastric anisakiasis in the West, this disease has become widely re...

normal 0 false false false en-us x-none ar-sa background: gastric carcinoma is the second most common cause of cancer-related death in iran. it is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin 17 (g-17), pepsinogen i (p-i), and pepsinogen ii (p-ii). the aim of this study was to investigate the diagnostic ac...