نتایج جستجو برای: gastric cancers
تعداد نتایج: 192273 فیلتر نتایج به سال:
Background: Gastrointestinal Cancers are one of the most important causes of mortality of patients in the world as well as in our country. The North of Iran is in Asian belt of esophagus cancer in addition, in other areas of our country gastric cancer is the most common GI Cancer. Because GI Cancers are common in Lorestan, we decided to study them in patients undergo endoscopy and colonoscopy i...
Gastric cancer is the world's second most common cause of cancer death. We analyzed gene expression patterns in 90 primary gastric cancers, 14 metastatic gastric cancers, and 22 nonneoplastic gastric tissues, using cDNA microarrays representing approximately 30,300 genes. Gastric cancers were distinguished from nonneoplastic gastric tissues by characteristic differences in their gene expression...
BACKGROUND The risk of developing a second primary tumour in patients with gastric carcinoma is higher than among the general population. The aim was to investigate the clinicopathological characteristics of the second primary cancers in patients with gastric cancer in this study. PATIENTS AND METHODS In the retrospective study, patients with gastric cancers were evaluated between 1995 and 20...
Nutrition in gastrointestinal (GI) cancer is an important part of treatment protocol. A detailed study published guidelines necessary to prevent pre-operative malnutrition and sustain peri-operative nutrition such patients. In this review, we discuss propose recommendations based on established suit the Indian population with different GI cancers (gastric, esophageal, pancreatic, colorectal hep...
Objective: The mutation in the promoter region of telomerase reverse transcriptase (TERT) has been focused in various cancers. In present study, the frequency and clinical characteristics of TERT promoter mutation, telomere length, and TERT expression in gastric cancers were studied. Materials and Methods: We sequenced TERT promoter region in 104 gastric cancers. And telomere length and TERT ex...
Microsatellite instability (MSI) within coding regions causes frameshift mutations (FSMs). This type of mutation may inactivate tumor suppressor genes in cancers with frequent MSI (MSI-H cancers). To identify novel FSMs in gastric carcinogenesis in an unbiased and comprehensive manner, we screened for this type of mutation at 154 coding region repeat loci in 18 MSI-H gastric cancers. We also co...
Introduction & Objective: Gastric cancer is one of the most common cancers in Iran, and in some regions, the prevalence of this cancer is the highest among all diagnosed cancers, also it has the highest mortality rate. Concerning to different tumoral mutations that have role in prognosis and type of treatments in different cancers, this study was done to determine the association between p53 ...
BACKGROUND Gastric cancers with microsatellite instabilities (MSI) have been reported to be associated with favorable prognosis. However, the significance of the effect of MSI on the clinicopathological features, as well as its association with mucin phenotype, remains unclear. METHODS MSI status was assessed in 414 cases of gastric cancer using polymerase chain reaction analysis of five micr...
All gastric carcinomas are originated from foveolar (stem/basal) cells, in practice. The most important development in this field is the detection of H.pylori’s role in the development of chronic gastritis as an important etiological factor. In most examples, they develop on the ground of intestinal metaplasia and chronic atrophic gastritis, and led by various stages of dysplasia, carcinoma in ...
CD133 is considered as a stem-like cell marker in some cancers including gastric cancers, and Notch1 signaling is known to play an important role in the maintenance and differentiation of stem-like cells. We aimed to investigate whether Notch1 signaling contributes to the carcinogenesis of gastric cancers and CD133 induction. CD133 expression was detected in 51.4% of diffuse type gastric cancer...
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