BACKGROUND AND OBJECTIVES Venous thromboembolism (VTE) occurs in 7%-40% of nephrotic patients. The risk of VTE depends on the severity and underlying cause of nephrotic syndrome. This study investigated the use of low-dose prophylactic anticoagulation to prevent VTE in patients with nephrotic syndrome caused by primary glomerulonephritis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Since 20...

BACKGROUND Dual antiplatelet therapy (DAPT) has been found to reduce the risk of cardiac death, myocardial infarction, stroke, and stent thrombosis following acute coronary syndrome and percutaneous coronary intervention. However, this therapy has also been shown to increase the risk of gastrointestinal (GI) bleeding as high as 2-fold, especially in patients with multiple risk factors. Proton p...

gastrointestinal stromal tumors (gist) are the most common mesenchy­mal tumors of the gastrointestinal tract. the biological pattern of these tumors ranges from benign-appearing small lesions to malignant sarcomas. only 3%-5% of gists are found in the duodenum. a duodenal gist is a rare source of upper gastrointestinal bleeding. a remarkable percentage of duodenal gists are localized in the thi...

background upper gastrointestinal bleeding (ugib) is a major healthcare problem and is the most frequent gastrointestinal reason for admission to hospital. we aimed to investigate the prognosis of patients with ugib referred to a referral hospital in northern iran in 2013. methods all patients with ugib who admitted to sayyad shirazi hospital, in gorgan, northern iran, in 2013 were enrolled. th...

â  a 56 year-old man with recurrent gastrointestinal bleeding is reported. the patient had constant crampy pain in his epigastrium, right upper quadrant and periumbilical area. upper-gastrointestinal endoscopy was normal. colonoscopy showed a soft-tissue mucoâ­sal lesion in the rectum which was determined to be a worm that extended into the lumen of the rectum with no bleeding. the pathology wa...

conclusion superselective tae for lgi bleeding has a high success and low complication rate. there are no statistical correlations between the clinical success rate and several variables, including embolic material, embolization site, and anticoagulant or antiplatelet medication. patients and methods fifty-two patients who underwent superselective tae for lgi bleeding between 2003 and 2011 were...

BACKGROUND Proton pump inhibitors are often used in critically ill patients to prevent gastrointestinal bleeding despite limited evidence for benefit. Patients with acute kidney injury requiring renal replacement therapy (RRT) are at high risk of gastrointestinal bleeding as (pre-)uremia induces coagulopathy through effects on platelets and coagulation cascades. No high-quality randomized clini...

AIM OF THE STUDY Despite widespread use of pharmacological prophylaxis, venous thromboembolism (VTE) still constitutes a common complication in cancer patients. The aim of the study was to analyse the safety of low-molecular-weight heparins (LMWH) in the prevention of VTE in surgically-treated cancer patients. MATERIAL AND METHODS A total of 5207 cancer patients (44.5% men and 55.5% women) ag...

BACKGROUND The term stress-related mucosal disease (SRMD) represents a continuum of conditions ranging from stress-related injury (superficial mucosal damage) to stress ulcers (focal deep mucosal damage). Caused by mucosal ischemia, SRMD is most commonly seen in critically ill patients in the intensive care unit (ICU). Prophylaxis of stress ulcers may reduce major bleeding but has not yet been ...

BACKGROUND The widespread use of gastrointestinal bleeding prophylaxis in critically ill patients was one of the most controversial issues. Since few studies reported the incidence of gastrointestinal bleeding in mechanically ventilated patients, this study aimed to identify the incidence and risk factors related to gastrointestinal bleeding in patients undergoing mechanical ventilation for mor...