نتایج جستجو برای: gdap1

تعداد نتایج: 91  

2011
Jonathan Baets Tine Deconinck Els De Vriendt Magdalena Zimoń Laetitia Yperzeele Kim Van Hoorenbeeck Kristien Peeters Ronen Spiegel Yesim Parman Berten Ceulemans Patrick Van Bogaert Adolf Pou-Serradell Günther Bernert Argirios Dinopoulos Michaela Auer-Grumbach Satu-Leena Sallinen Gian Maria Fabrizi Fernand Pauly Peter Van den Bergh Birdal Bilir Esra Battaloglu Ricardo E. Madrid Dagmara Kabzińska Andrzej Kochanski Haluk Topaloglu Geoffrey Miller Albena Jordanova Vincent Timmerman Peter De Jonghe

Early onset hereditary motor and sensory neuropathies are rare disorders encompassing congenital hypomyelinating neuropathy with disease onset in the direct post-natal period and Dejerine-Sottas neuropathy starting in infancy. The clinical spectrum, however, reaches beyond the boundaries of these two historically defined disease entities. De novo dominant mutations in PMP22, MPZ and EGR2 are kn...

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2007

Journal: :Brain : a journal of neurology 2007
Ahmed Bouhouche Nazha Birouk Hamid Azzedine Ali Benomar Garry Durosier Dorothée Ente Marie-Paule Muriel Merle Ruberg Ilham Slassi Mohamed Yahyaoui Odile Dubourg Reda Ouazzani Eric LeGuern

Charcot-Marie-Tooth disease is a genetically heterogeneous group of hereditary motor and sensory neuropathies. Three loci for the axonal autosomal recessive subgroup (ARCMT2) have been reported in 1q21 (CMT2B1, LMNA), 8q21 (CMT4A and CMT2K, GDAP1) and 19q13 (CMT2B2). We report here a clinical, electrophysiological, pathological and genetic study in 13 Moroccan families with ARCMT2 phenotypes. C...

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