Background:  Widespread and growing sources of electromagnetic radiation raised concerns attributed to the potential adverse health risk of radiofrequency fields. Given the functional importance of the hippocampus, this study aimed to investigate the effects of electromagnetic waves radiated by mobile jammer on hippocampal expression of p21 and p53 genes as regulators of cellular apoptosis...

Background: DNA microarray is a useful technology that simultaneously assesses the expression of thousands of genes. It can be utilized for the detection of cancer types and cancer biomarkers. This study aimed to predict blood cancer using leukemia gene expression data and a robust ℓ2,p-norm sparsity-based gene selection method. Materials and Methods: In this descriptive study, the microarray ...

Background: The aim of this study was evaluation of developmental rate and Bax, Bcl-2 and ErbB4 genes expression following re-vitrification in compact and early blastocysts stages. Materials and Methods: 5-8 cell embryos were collected from female mature mice, 60-62 hours post hCG injection. The embryos were divided to five groups including: fresh, vitrified at 5-8 cells, vitrified at blastocys...

background: with the increasing concern for health and nutrition, dietary fat has attracted considerable attention. the composition of fatty acids in the diet is important because they are associated with major diseases including cancers, diabetes, and cardiovascular disease. the fatty acid synthase (fasn) and stearoyl-coa desaturase (delta-9-desaturase) (scd) genes affect fatty acid compositio...

Real time-qPCR is the most reliable method for evaluation of mRNA expression levels. However, to obtain accurate results, selection of suitable reference genes is necessary for normalizing the real-time qPCR data. The aim of this research was to validate the expression stability of three potential reference genes (ACTB, GAPDH and UXT) in milk somatic cells of Holstein dairy cattle under differe...

Background MIF via its receptor, CD74, initiates a signaling cascade that leads to proliferation and survival of cells. Also, MIF binding to CD74 activates p38 signaling pathways that lead to positive effect on the expression of COX-2. The aim of this study was to evaluate the gene expression profile of MIF, CD74 and COX-2 in normal, ectopic and eutopic endometrium during menstrual cycle. The e...

Trehalose is the non-reducing alpha-alpha-1, 1-linked glucose disaccharide. The biosynthesisprecursor of trehalose, trehalose-6-phosphate (T6P), is essential for plant development, growth,carbon utilization and alters photosynthetic capacity but its mode of action is not understood. In thecurrent research, 6 days old seedlings of Arabidopsis thaliana (Columbia ecotype) were grown inliquid cultu...

stress is one of the effective factors in the development of depressive disorders that performs some parts of its effects by affecting hippocampus. since doxepin has been shown to have neuroprotective effects, in this study, we focused on the effects of doxepin on the expression of involved genes in neuronal survival and plasticity in the rat hippocampus following chronic stress. male wistar ra...