Genetic mapping (also known as linkage mapping or meiotic mapping) refers to the determination of the relative position and distances between markers along chromosomes. Genetic map distances between two markers are defined as the mean number of recombination events, involving a given chromatid, in that region per meiosis. Genetic map construction requires that the researcher develop appropriate...

Genetic mapping and positional cloning of genetically complex traits in the laboratory rat (Rattus norvegicus) has recently led to the identification of various susceptibility genes in different rat models. Rat genetics has benefited from revolutionary advances in molecular biology, genetics, genomics and informatics and provide an unparalleled resource for molecular genetic investigation of ma...

Genetic mapping provides a powerful approach to identify genes and biological processes underlying any trait influenced by inheritance, including human diseases. We discuss the intellectual foundations of genetic mapping of Mendelian and complex traits in humans, examine lessons emerging from linkage analysis of Mendelian diseases and genome-wide association studies of common diseases, and disc...

Tomato (Solanum lycopersicum) has a high level of genetic variation in fruit color, which is an important quality trait considered by breeders and consumers. The stripe color pattern determined the green (gs) locus observed only peel tissue tomato. Using two different F2 populations (351 97 individuals), we mapped gs to long arm chromosome 7 found that it cosegregated with TOMATO AGAMOUS-LIKE 1...