Despite progress in diabetes care and treatment, pregnancies in women with either type 1 or, type 2 DM are still associated with poorer outcomes with respect to healthy non diabetic women. Pregestational DM complicates 0.2 - 0.6% of pregnancies, 35% had type1 and 66% had type 2 DM. In contrast to GDM, pre GDM is more serious because the potential effects of uncontrolled glycemic levels begins a...

Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees that is first detected during pregnancy. GDM is detected through the screening of pregnant women for clinical risk factors and, among at-risk women, testing for abnormal glucose tolerance that is usually, but not invariably, mild and asymptomatic. GDM appears to result from the same broad spectrum of physio...

Prepregnancy overweight or obesity and excessive gestational weight gain have been associated with increased risk of maternal and neonatal complications. Moreover, offspring from obese women are more likely to develop obesity, diabetes mellitus, and cardiovascular diseases in their lifetime. Gestational diabetes mellitus (GDM) is one of the most common complications associated with obesity and ...

Gestational diabetes mellitus (GDM) and obesity in pregnancy (OP) are pathological conditions associated with placenta vascular dysfunction coursing with metabolic changes at the fetoplacental microvascular and macrovascular endothelium. These alterations are seen as abnormal expression and activity of the cationic amino acid transporters and endothelial nitric oxide synthase isoform, that is, ...

INTRODUCTION Understanding patterns of diabetes prevalence and diabetes-related complications across pregnancies could inform chronic disease prevention efforts. We examined adverse birth outcomes by diabetes status among women with sequential, live singleton deliveries. METHODS We used data from the 1998-2007 Massachusetts Pregnancy to Early Life Longitudinal Data System, a population-based ...

In order to enhance cost-benefit value of the gestational diabetes mellitus screening (GDM) concept universal i.e., all pregnant women for diabetes, has mostly been abandoned in favor selective screening. Selective implies that only with risk factors are being screened GDM. However, some recent studies have shown application approach, GDM may not receive proper and timely diagnosis. This review...

OBJECTIVE The International Association of Diabetes in Pregnancy Study Groups (IADPSG) criteria for diagnosis of gestational diabetes mellitus (GDM) identifies women and infants at risk for adverse outcomes, which are also strongly associated with maternal overweight, obesity, and excess gestational weight gain. RESEARCH DESIGN AND METHODS We conducted a retrospective study of 9,835 women who...

objective: low-grade systemic inflammation is associated with an increased risk of type 2 diabetes. c-reactive protein (crp), an acute phase protein produced by hepatocytes, may be associated with diabetes. this study aimed to compare serum levels of crp in women with gestational diabetes mellitus (gdm), impaired glucose tolerance test and control subjects. materials and methods: in this case c...

OBJECTIVE The objective of the study was to report the socio demographic risk factors of gestational diabetes mellitus (GDM). METHODS This study was conducted in the Institute of Chemical Sciences, University of Peshawar. In this study 103 GDM and 97 healthy pregnant women (HPW) were registered in Khyber Teaching Hospital (KTH), Peshawar, Pakistan. Women with gestational diabetes were diagnos...

OBJECTIVE: Low-grade systemic inflammation is associated with an increased risk of type 2 diabetes. C-Reactive Protein (CRP), an acute phase protein produced by hepatocytes, may be associated with diabetes. This study aimed to compare serum levels of CRP in women with gestational diabetes mellitus (GDM), impaired glucose tolerance test and control subjects. MATERIALS AND METHODS: In this ca...