BACKGROUND Impairment of cognitive function as well as negative symptom is the major factor causing the decline of a patient's functioning in chronic stages of schizophrenia. However, until now, there were no definite treatment options that could effectively reduce the impairment. CASE PRESENTATION We report a case of mood dysregulation associated with use of Ginkgo biloba in a patient with s...

the entomopathogenic fungus beauveria bassiana (bals.) vuill. is one of the important arthropod pathogens that can play an important role in the regulation of mite populations in agricultural ecosystems. in this study, the combined effect of a native isolate of fungus b. bassiana (eut105) and ether-extract of plant, ginkgo biloba was evaluated against the two-spotted spider mite, tetranychus ur...

introduction: many people with amnesia would like to try herbal therapies. ginkgo biloba is one of the most popular herbs which is used to treat amnesia. the beneficial effects of this plant, however, has not been scientifically assessed yet. although, there have been some reports on the memory enhancement effect of ginkgo biloba, the mechanism of its action is not yet explained well. consideri...

The objective of the study was to evaluate the antidiabetic activity of Ginkgo biloba and to probe into its mechanism of action. Methods. Albino wistar rats with streptozotocin induced diabetes were divided into 4 groups of 10 each. Gum acacia, troglitazone 36 mg/kg, Ginkgo biloba 50 mg/kg and 100 mg/kg, were administered to group I (control), group II (standard), group III and group IV respect...

OBJECTIVE This analysis was to assess the long-term clinical and economic implications of galantamine in the treatment of mild-to-moderate Alzheimer's disease (AD) in Germany. METHODS An economic model was developed using discrete event simulation to predict the course of AD through changes in cognition, behavioural disturbance, and function over time. It compares the costs and benefits of ga...

OBJECTIVE To evaluate the efficacy of Ginkgo biloba as a complementary therapy for attention-deficit/hyperactivity disorder (ADHD). METHODS Children and adolescents with ADHD received methylphenidate (20-30 mg/day) plus either G. biloba (80-120 mg/day) or placebo for 6 weeks. Parent and teacher forms of the ADHD Rating Scale-IV (ADHD-RS-IV) were completed at baseline, week 2, and week 6. Trea...

Objective: This study investigated the possible neuroprotective effects of Ginkgo biloba on cerebral ischemia-reperfusion (I/R) injury in ovariectomized rats. Methods: Rats were randomly allocated into 5 groups as follows: Sham-operated group, Ovariectomized group (OVX), Cerebral I/R injury ovariectomized group (OVX+I/R) and two treated groups given Ginkgo biloba leaves extract in two doses [(O...

In the present study, we investigated the effect of Ginkgo biloba extracts and some of its individual constituents on the catalytic activity of human cytochrome P450 enzymes CYP1B1, CYP1A1, and CYP1A2. G. biloba extract of known abundance of terpene trilactones and flavonol glycosides inhibited 7-ethoxyresorufin O-dealkylation catalyzed by human recombinant CYP1B1, CYP1A1, and CYP1A2, and human...

Objectives/Goals Pharmaceutical companies have marketed Ginkgo biloba leaf extracts as a memory and concentration enhancer as well as a treatment for Alzheimer's disease and dementia patients. However, there have been numerous studies with varying results about the benefits of G. biloba. My objective was to determine whether G. biloba affects synaptic plasticity via cytoskeletal protein concent...

INTRODUCTION Tinnitus is one of the common diseases of the ear that is associated with numerous physical and mental disorders. One of the known mechanisms in the tinnitus area with unknown reason is oxidative events. Based on the prevalence and economic costs and physical- psychological side effects caused by tinnitus and the importance of finding a suitable solution for its prevention and trea...