BACKGROUND The World Health Organization's Global Burden of Disease (GBD) reports are an important tool for global health policy makers, however the accuracy of estimates for countries undergoing an epidemiologic transition is unclear. We attempted to validate the life table model used to generate estimates for all-cause mortality in developing countries. METHODS AND RESULTS Data were obtaine...

BACKGROUND Tick-borne encephalitis (TBE) presents an increasing burden in many parts of Europe, Asian Russia, Siberia, Asian former USSR and Far East. Incidence can be considered as one way to express the burden. A more comprehensive measure concerns disability-adjusted life years (DALYs), better characterizing the full burden of TBE. TBE burden in DALYs has not yet been estimated, nor has it b...

disease attributable to individual risk factors were calculated, as described in chapter 25, using risk factor exposure and hazard estimates provided in risk factor chapters. Mortality and burden of disease attributable to individual risk factors were then calculated by multiplying the PAFs by the estimates of total mortality and burden of disease from the Global Burden of Disease (GBD) databas...

OBJECTIVES We sought to determine whether disease representation in the Cochrane Database of Systematic Reviews (CDSR) reflects disease burden, measured by the Global Burden of Disease (GBD) Study as disability-adjusted life-years (DALYs). MATERIALS AND METHODS Two investigators performed independent assessment of ten men's health and urologic diseases (MHUDs) in CDSR for systematic review an...

Background. Although 80% of the burden of cardiovascular disease (CVD) is in developing countries, the 2010 global burden of disease (GBD) estimates have been cited to support a premise that sub-Saharan Africa (SSA) is exempt from the CVD epidemic sweeping across developing countries. The widely publicized perspective influences research priorities and resource allocation at a time when secular...

BACKGROUND Previous global burden of disease (GBD) estimates for household air pollution (HAP) from solid cookfuel use were based on categorical indicators of exposure. Recent progress in GBD methodologies that use integrated-exposure-response (IER) curves for combustion particles required the development of models to quantitatively estimate average HAP levels experienced by large populations. ...

AIMS The purpose of this study was to determine the international commitment to alcohol-related research relative to its global burden of disease, which is 4% of disability adjusted life years (DALYs). METHODS The worldwide literature indexed in the Science Citation Index and the Social Sciences Citation Index during 1992-2003 was analysed using advanced bibliometric techniques. RESULTS Bio...

We have recently embarked on a collaborative project to improve estimates of the global burden of injuries. This commentary invites individuals and organizations to contribute to building this global public good by providing the project access to relevant results from local injury data sources. Reliable estimates of the incidence and burden of injuries are essential inputs for prioritizing prev...