Our previous studies show that a decrease in endogenous nitric oxide (NO) is involved in the blunted outward K(+) currents in carotid body (CB) glomus cells from chronic heart failure (CHF) rabbits. In the present study, we measured the effects of the neuronal nitric oxide synthase (nNOS) transgene on the K(+) currents in CB glomus cells from pacing-induced CHF rabbits. Using single-cell real-t...

BACKGROUND Glomus tumors have recently been reported in individuals with the neurofibromatosis type 1 (NF1) cancer disposition syndrome. We compare the clinical and molecular features of these painful hamartomas in a series of sporadic and NF1-associated cases. OBJECTIVE We sought to evaluate the association of NF1 with glomus tumors and to compare NF1-associated glomus tumors with sporadic g...

BACKGROUND Glomus tumor is an uncommon neoplasm derived from cells of the neuromyoarterial glomus or glomus body. Most glomus tumours occur in the dermis and subcutaneous tissues. A case of a primary pulmonary glomus tumour originating in the right upper lobe is presented. CASE PRESENTATION A 74-yr-old male was admitted with siccus cough, dyspnea and right-sided chest pain. Computed tomograph...

Roy, Arijit, Jinqing Li, Abu-Bakr Al-Mehdi, Anil Mokashi, and Sukhamay Lahiri. Effect of acute hypoxia on glomus cell Em and m as measured by fluorescence imaging. J Appl Physiol 93: 1987–1998, 2002. First published August 2, 2002; 10.1152/japplphysiol.00725.2001.—We have reinvestigated the hypothesis of the relative importance of glomus cell plasma and mitochondrial membrane potentials (Em and...

Glomangiomas (glomus tumours) are uncommon, and in most cases are benign perivascular tumours, usually located in the dermis of the extremities, especially in the subungual region of the fingers. They also occur in other organs and in other regions of the body. Histogenetically, they are derived from modified smooth muscle cells of the glomus apparatus, which is associated with temperature regu...

Glomangioma is very rare lesion in extradigital location. They are usually associated with multiple and familial lesion. Glomangioma as with glomus tumour also presents with hypersensitivity to cold, severe pain and pinpoint tenderness to blunt palpation. Glomus tumours have not been observed in individuals who are less than one year of age (glomus bodies form after that age) or in elderly pers...

Glomangiomas are a variant of benign glomus tumours; glomus tumours are benign neoplastic proliferations of the glomus body, which is made up of perivascular smooth muscle cells. This forms arteriovenous anastomoses which play an important role in vascular regulation of skin temperature. The aim of this article is to describe 2 cases of hereditary glomangiomas.

Glomus tumors showing nuclear pleomorphism without any other malignant features have been defined as symplastic glomus tumors. This type of glomus tumor is rarely encountered. Another case of symplastic glomus tumor is described in this study. A 37-year-old woman referred to the hospital with the complaint of a palpable tender nodule on the fourth finger tip of her left hand. The lesion had bee...

Most glomus tumours occur in the dermis and subcutaneous tissues. Lung glomus tumours are quite rare. The current authors present the first reported case of a lung-derived glomangiomyoma, the rarest variant of glomus tumour. A 56-yr-old female was admitted with haemoptysis. Chest computed tomography showed an ,5-cm-diameter mass in the right lower lobe with mucoid impaction. After a right lower...