Due to the lack of unequivocal scientific evidence, gonadectomy’s effects on dogs’ behavior are still debated. Since veterinarians differ in their opinion, there may be considerable diversity advice received by owners. This study aimed evaluate gonadectomy dog across time. Ninety-six owners (48 control dogs and 48 experimental dogs) were interviewed twice (T0 T1, nine months later) obtain infor...

The effects of gonadectomy on the epidermal growth factor (EGF) concentrations in the gastrointestinal tract of CD-1 mice were studied. The EGF concentrations in the gastrointestinal tissues were always higher in males than in females. Gonadectomy led to a decrease in the EGF concentration in males, and an increase in females. Gonadectomy with sialoadenectomy led to a decrease in the EGF concen...

Prophylactic gonadectomy has been recommended in complete androgen insensitivity syndrome (CAIS) because of an increased risk for the development of malignant germ cell tumors in the intra-abdominal gonads. No reliable screening parameters are available to detect early (pre-)malignant changes. Because the tumor risk before puberty is very low, the timing of gonadectomy has been postponed to all...

MAIN FINDINGS A 22-year-old woman with complete androgen insensitivity syndrome (CAIS) presenting with primary amenorrhea and normal female external genitalia was referred for laparoscopic gonadectomy. She had been diagnosed several years earlier but was reluctant to undergo surgery. Case HYPOTHESIS Diagnosis of this X-linked recessive inherited syndrome characterizes by disturbance of virili...

Neonatal gonadeetomy has been used in some inbred strains of mice (7, 8, 10, 13-17) as an experimental tool to study the effect of hormonal imbalance. ~I'he effect of neonatal gonadectomy in reciprocal hybrid mice of several inbred strains has been described (11, 1~). This paper will report the response to gonadectomy of the F1 animals of strain DE X strain DBA and will compare the response of ...

A 16-year-old female patient presented with complaints of amenorrhea and lack of breast development. Baseline hormonal results were consistent with primary ovarian failure. Ovaries and uterus could not be demonstrated by ultrasonographic evaluation. No deletion-type mutation was detected in the SRY gene of the patient whose karyotype was 46, XY. The gonads, both of which were detected as streak...

In general, there is a relationship between growth and reproduction, and gonads are known to be important organs for growth, but direct evidence for their role is lacking. Here, using a fish model, we report direct evidence that gonads are endocrine organs equal to the pituitary in controlling body growth. Gonadal loss of function, gain of function, and rescue of growth were investigated in til...

Gonadoblastoma and dysgerminoma developed in a 24-year-old phenotypic female patient with 46,XY pure gonadal dysgenesis. This patient presented with primary amenorrhea. Clinical characteristics showed a typical stigmata of gonadal dysgenesis: primary amenorrhea, sexual infantilism, a small uterus and bilateral streak gonads. A 46,XY karyotype was made by lymphocyte culture. The patient was coun...