نتایج جستجو برای: gp73

تعداد نتایج: 112  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Timothy M Block Mary Ann Comunale Melissa Lowman Laura F Steel Patrick R Romano Claus Fimmel Bud C Tennant W Thomas London Alison A Evans Baruch S Blumberg Raymond A Dwek Tajinder S Mattu Anand S Mehta

Chronic infection with hepatitis B virus (HBV) is associated with the majority of hepatocellular carcinoma (HCC). The diagnosis of HCC is usually made in the late stages of the disease, when treatment options are limited and prognosis is poor. We therefore have developed a method of glycoproteomic analysis in an attempt to discover serum markers that can assist in the early detection of HBV-ind...

2017
Ni Zhou Kuifeng Wang Shanhua Fang Xiaoyu Zhao Tingting Huang Huazhong Chen Fei Yan Yongzhi Tang Hu Zhou Jiansheng Zhu

Hepatitis B virus (HBV)-associated acute-on-chronic liver failure (HBV-ACLF), characterized by an acute deterioration of liver function in the patients with chronic hepatitis B (CHB), is lack of predicting biomarkers for prognosis. Plasma is an ideal sample for biomarker discovery due to inexpensive and minimally invasive sampling and good reproducibility. In this study, immuno-depletion of hig...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009
Mengjun Wang Ronald E Long Mary Ann Comunale Omer Junaidi Jorge Marrero Adrian M Di Bisceglie Timothy M Block Anand S Mehta

Changes in glycosylation, most notably fucosylation, have been associated with the development of hepatocellular carcinoma (HCC). In this report, the levels of fucosylated kininogen (Fc-Kin) and fucosylated alpha-1-antitrypsin were analyzed individually and in combination with the currently used marker, alpha-fetoprotein, and a previously identified biomarker, Golgi protein 73 (GP73), for the a...

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