32 Two types of AQP5 genes (aqp-xt5a and aqp-xt5b) were identified in the genome of 33 Xenopus tropicalis by synteny comparison and molecular phylogenetic analysis. 34 When the frogs were in water, AQP-xt5a mRNA was expressed in the skin and urinary 35 bladder. The expression of AQP-xt5a mRNA was significantly increased in 36 dehydrated frogs. AQP-xt5b mRNA was also detected in the skin and inc...

BACKGROUND Granular cell tumor (GCT) is a benign soft tissue tumor of neural origin and is characterized by eosinophilic granular cells showing positivity for neuronal markers. Herein, we report the first case of primary intraosseous GCT arising in the maxilla of an adolescent girl. METHODS AND RESULTS A 16-year-old female patient presented with palatal swelling. Radiographic findings reveale...

Ameloblastoma is a neoplasm of odontogenic epithelium, especially of enamel organ-type tissue that has not undergone differentiation to the point of hard tissue formation. Granular cell ameloblastoma is a rare condition, accounting for 3.5% of all ameloblastoma cases that shows marked transformation in the cytoplasm of tumor cells, which are usually stellate reticulum like cells. It is also con...

Dasatinib, a dual tyrosine kinase inhibitor, is known to modulate or suppress T-cell activation and proliferation. We report a series of 8 patients who developed chronic peripheral lymphocytosis, identified as natural killer cells or natural killer/T-cells based on their large granular lymphocyte morphologies and CD16(+), CD56(+), CD3(-) or CD3(+) immunophenotypic profiles, out of 18 patients r...

Malignant granular cell tumor is a rare neural tumor characterized by abundant granular-appearing tumor cells. These tumors account for <2% of all granular cell tumors. Unlike its benign counterpart, a malignant granular cell tumor presents primarily in the lower limb and is notably larger. Both the uncommon occurrence of malignant granular cell tumors and its similarities in feature with their...

Electron microscopic studies were made of the parathyroid gland of quail aged 4 to 12 months. Most parenchymal cells consisted of chief cells. Sometimes, cells having numerous microfilaments, scant granular endoplasmic reticulum, a few mitochondria, a small Golgi apparatus, and long cell processes that extended between contiguous cells were located on a basal lamina. These cells may serve as su...

Granular cell tumors are uncommon soft tissue neoplasm of nerve sheath origin, which are predominately benign. Granular cells can be found at any site in the body including the tongue, skin, subcutaneous tissue, breast, gastrointestinal, and urogenital systems. However, granular cell tumors have only been rarely described in the chest wall. Here we report a case of a granular cell tumor that oc...

To analyze the degradation system in epidermal cells during their generation, differentiation, and cell death, immunocytochemical localization of lysosomal cysteine and aspartic proteinases, an endogenous cysteine proteinase inhibitor, cystatin beta, and ubiquitin were examined using rat sole skin. By confocal laser microscopy, granular immunodeposits for lysosomal proteinases were well demonst...