Lidocaine hydrochloride (Lido) is widely used for analgesia in veterinary medicine; however, in humans, it has been suggested that Lido attenuates granulocyte functions, such as adhesion and reactive oxygen species (ROS) production. Thus, Lido may affect canine granulocyte function; however, there have been no reports on the effects of Lido on canine granulocyte function. Thus, we studied the e...

The kinetics of neutrophilic granulocytes half disappearance time shortened to 2.3 hr. and monocytes were examined simulMoreover, the intravascular granulocyte dietaneously in a patient suffering from cyclic tribution changed in favor of the marginal neutropenia. During the remission phase of granulocyte pool. During the neutropenic the disease the observed kinetic data for phase, the intravasc...

Thirty episodes of infection in severely neutropenic children with acute leukaemia and aplastic anaemia resistant to antibiotics were treated with total of 51 granulocyte transfusions collected from normal donors by means of an Aminco continuous flow cell separator. The mean granulocyte increment in the recipients was 820/mm3 at 1 hour and 307/mm3 at 15 hours post-transfusion and it showed a co...

Since granulocyte transfusions first became widely used in clinical medicine, there have been advances in the treatment of acute leukemia and improvement in prevention and management of infection in neutropenic patients. Improved understanding now exists concerning prognosis of infections in such patients, and advances have been made in procurement of granulocytes. Granulocyte transfusions shou...

The use of biofloc technology (BFT) in narrow-clawed crayfish (Astacus leptodactylus) culture for 45 days was evaluated by production performance and physiological status crayfish. Four different stocking densities were tested BFT (20, 41.66, 62.5, 83.33 individuals m-2). Water quality parameters monitored to sustain desired levels management. growth did not show any significant differences amo...

This study aims to determine the relationship between hemocyte count and types with environmental variables morphometric measurements in Carcinus aestuarii. A total of 240 crabs were seasonally collected Çardak Lagoon June 2018, October February 2019, May 2019. The average carapace length (CL) was 44.66±0.44 mm, mean width (CW) 37.71±0.38 mm weight 28.49±0.88 g. Crab specimens anesthetized on i...

introduction: various neuroregenerative procedures have been recently employed along with neurorehabilitation programs to promote neurological function after spinal cord injury (sci), and recently most of them have focused on the acute stage of spinal cord injury. in this report, we present a case of acute sci treated with neuroprotective treatments in conjunction with conventional rehabilitati...

The transfusion of neutrophils, or granulocyte transfusion therapy, has long been considered as a logical approach to the treatment of severe bacterial and fungal infections in patients with prolonged neutropenia or intrinsic defects in neutrophil function. However, despite numerous clinical trials, the efficacy and safety of granulocyte transfusion therapy remain controversial. Efficacy has be...

background: immunotoxins are comprised of both the cell targeting and the cell killing moieties. we previously established a new immunotoxin, i.e. shiga toxin granulocyte macrophage-colony stimulating factor (stxa1-gm-csf), comprises of catalytic domain of stx, as a killing moiety and gm-csf, as a cell targeting moiety. in this study, the ability of the immunotoxin to induce apoptosis and doubl...

In murine leukemia virus-induced myeloid leukemias, insertional mutagenesis of the c-myb locus has been shown to occur frequently. Proto-oncogene activation is achieved in most leukemias by integration of murine leukemia virus upstream of exons 3 or 4 or by integration into exon 9 with consequent truncation of the protein. The present study investigates the effect of ectopic expression of full-...