Beta-blockers are effective hypotensive agents in Caucasians. In a double-blind cross-over trial on 18 hypertensive Jamaicans, however, Humphreys and Delvin found no significant difference between propranolol and an inert placebo.2 This was not confirmed by Grell in an open study of the drug.3 I reported control of blood pressure with propranolol in eight out of 12 Indians and only four out of ...

Abstract. The Weather Research and Forecasting (WRF) model offers a multitude of physics parameterizations to study analyze the different atmospheric processes dynamics that are observed in Earth's atmosphere. However, suitability WRF setup is known be highly sensitive type weather phenomena combination parameterizations. A multi-event sensitivity analysis conducted identify general trends suit...

High spatiotemporal resolution climate data are essential for climate-related impact studies. The Weather Research and Forecasting (WRF) model is widely used to downscale different regions with regional-specific physics configurations. This study aimed identify robust configurations of the WRF model, especially cumulus parameterization schemes, climatic zones Sudan. We focused on wet season (Ju...

HE distributive pairing hypothesis of GRELL (1962) aims to elucidate the Tmechanisms involved in chromosome pairing, exchange, and disjunction at meiosis in the female of Drosophila melanogaster. It provides a new interpretation of meiosis which can account for many of the seemingly contradictory reports on chromosome behaviour made by earlier authors. Former ideas on the nature of pairing and ...

HE relation between crossing-over and disjunction in the Drosophila female Thas been studied for many years. ANDERSON (1929), DOBZHANSKY (1932, 1933), BROWN (1940), PIPKIN ( 1940) and others clearly demonstrated that crossing-over has a strong influence on disjunction in translocation heterozygotes. The reciprocal products of an exchange tend to pass to opposite poles of the first meiotic divis...

GRELL ( 1962a) has made the remarkable observations that, in Drosophila, R*chromosomes involved in nonhomologous (heterologous) pairing in a variety of configurations are derived entirely from the no-exchange class of tetrad and that the frequency of that class is not altered appreciably. This is contrary to the expectation that heterologous pairing, where possible, would generally compete with...

The sensitivity of different cumulus physical parameterization schemes for simulating extreme winter precipitation events over the Arabian Peninsula (AP) is investigated using a high-resolution weather research and forecasting (WRF) model. For winters in 2001–2016, following three are examined: (i) Kain–Fritsch (KF), (ii) Betts–Miller–Janji? (BMJ), (iii) Grell–Freitas (GF). simulation results s...

during those decades. On so general a level, of course, this point has been well articulated before, for example by Henry Kamen's The iron century (originally published in 1971). The authors depart from standard narratives, however, in emphasizing the ways in which certain early modem societies managed to escape the Malthusian dilemma of ever-increasing population and limited food supplies. The...

of "calling" in early seventeenth-century Denmark not only shaped Bartholin's theology, he argues, but also his medicine (p. 78). One of the strands in the story that Grell weaves is the relationship between Providence and physick: "what use ... is dittany and panacea?" Bartholin asks, "if God is not present and pours strength into herbs" (p. 79). This theme forms the focus of David Harley's st...