نتایج جستجو برای: growth factor α

تعداد نتایج: 1587363  

خردمند, فاطمه , روشن میلانی , شیوا , نوری , فرزانه, هاشم‌نیا , سیدمحمدرضا ,

  Background & Aims : Cancer cells proliferation may be mediated by abnormal phosphorylation of signaling pathways downstream of tyrosine kinase receptors such as Platelet derived growth factor receptor α (PDGFR-α) and β (PDGFR-β). We aimed to study the phosphorylation level of PDGFR-α and PDGFR-β and apoptosis in mouse normal leydig cells being exposed to Imatinib.   Materials & Methods : The ...

Journal: :Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2015
Mafaz Ullah Stephen Cox Elizabeth Kelly Malcolm A S Moore Hans Zoellner

BACKGROUND Areca nut chewing is associated with oral submucous fibrosis (OSF). Raised vascular basic fibroblast growth factor may induce fibrosis. Arecoline is a muscarinic alkaloid in areca nut, which we earlier reported causes injury and necrosis of human endothelium. MATERIALS AND METHODS Human umbilical vein endothelial cells were exposed to arecoline with or without tumor necrosis factor...

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