Deoxyribonucleic acid (DNA) is an important molecular target for anti-cancer agents due to its involvement in gene expression and protein synthesis which are fundamental steps in cell division and growth. A number of antineoplastic agents interfere with DNA and hence disturb the cell cycle. Compounds including planar aromatic rings are privileged scaffolds in binding to the DNA. This characteri...

The purpose of this study was to define early events during the angiogenic response of the aortic wall to injury. Rat aortic rings produced neovessels in collagen culture but lost this capacity over time. These quiescent rings responded to vascular endothelial growth factor but not to a mixture of macrophage-stimulatory cytokines and chemokines that was angiogenically active on fresh rings. Ana...

Introduction The study of tree rings is one of the most widely used methods of climate reconstruction for centuries and millennia, but the occurrence of climatic anomalies such as global warming in recent decades has caused divergence problem in the series of tree rings in some areas. Which challenges the ability of this proxy to regenerate the climate. The “divergence problem” is the differen...

in this study, we aimed to reconstruct the mean, maximum mean and ‎minimum mean temperature from the chronology of tree rings width of two ‎quercus persica sites in dena region, where efficient climatic data have a ‎short period (1982-2011). the duration of common chronology of the sites ‎is 131 years (1881-2011).considering the strong correlation between ‎climatic data and growth rin...

We know surprisingly little about whole-tree nonstructural carbon (NSC; primarily sugars and starch) budgets. Even less well understood is the mixing between recent photosynthetic assimilates (new NSC) and previously stored reserves. And, NSC turnover times are poorly constrained. We characterized the distribution of NSC in the stemwood, branches, and roots of two temperate trees, and we used t...

Deoxyribonucleic acid (DNA) is an important molecular target for anti-cancer agents due to its involvement in gene expression and protein synthesis which are fundamental steps in cell division and growth. A number of antineoplastic agents interfere with DNA and hence disturb the cell cycle. Compounds including planar aromatic rings are privileged scaffolds in binding to the DNA. This characteri...

In this paper we present an algorithm for the detection of fish otolith growth rings based on a graph construction method. The identification of growth rings, for age estimation, is routinely achieved in fishery laboratories by human readers. One of the major problem encountered during an automatic image processing is the lack of ring continuity perception. We present an approach to this contin...

Provenance studies are an increasingly important analog for understanding how trees adapted to particular climatic conditions might respond to climate change. Dendrochronological analysis can illuminate differences among trees from different seed sources in terms of absolute annual growth and sensitivity to external growth factors. We analyzed annual radial growth of 567 36-year-old pitch pine ...