surgical site infections are one of the most important post-surgery complications. antimicrobial prophylaxis has been used routinely in surgeries to reduce infection incidence. however, inappropriate selection of antimicrobial agents or dosing can develop antimicrobial resistance, serious adverse reactions and prolong hospitalization. current study aimed to examine prophylactic antibiotic presc...

purpose: to customize clinical practice guidelines (cpgs) for cataract management for iranian population. methods: first, four cpgs (american academy 2006 and 2011, royal college of ophthalmologists 2010 and canadian ophthalmological society evidence-based clinical practice guidelines 2008) were selected from a number of available cpgs for cataract management in the literature. second, all reco...

QUESTIONS In patients with inoperable locally advanced or metastatic soft tissue sarcoma, does first-line dose-intensive chemotherapy supported by growth factor or autologous bone marrow or stem-cell transplantation improve response rate, time to disease progression, or survival as compared with standard-dose chemotherapy? What are the effects of first-line dose-intensive chemotherapy supported...

von Willebrand disease (VWD) is the commonest inherited bleeding disorder. The aim of therapy for VWD is to correct the two defects of haemostasis in this disorder, impaired primary haemostasis because of defective platelet adhesion and aggregation and impaired coagulation as a result of low levels of factor VIII. The objective of this guideline is to inform individuals making choices about the...

Venous thromboembolism (VTE) is a common event in cancer patients and one of the major causes of cancer-associated mortality and a leading cause of morbidity. In recent years, the incidence rates of VTE have notably increased; however, VTE is still commonly underestimated by oncologists. VTE is considered an adverse prognostic factor in cancer patients in all settings. In 2011 the Spanish Socie...

background: knee pain is one of the most common reasons patients visit their physician. in this regard magnetic resonance imaging (mri) is the tool of preference for diagnosis. the aim of this study was to determine appropriate guidelines for knee mri administration using the rand appropriateness method (ram)-2013   methods: this qualitative study was done in the mashhad university of medical s...

to evaluate physical activity of pregnant women before and after acog guideline study. four hundred and eighty-five pregnant women enrolled in this before-after study. they were asked to study acog guideline. a structured questionnaire filled by women at first visit and the last visit in the prenatal clinic.type, frequency, duration and anxiety about doing exercises during pregnancy period. bef...

considering the nature of qualitative studies, the interaction between researchers and participants can be ethically challenging for the former, as they are personally involved in different stages of the study. therefore, formulation of specific ethical guidelines in this respect seems to be essential. the present paper aimed to discuss the necessity to develop explicit guidelines for conductin...

Cough is one of the most common symptom of many respiratory diseases. The Korean Academy of Tuberculosis and Respiratory Diseases organized cough guideline committee and cough guideline was developed by this committee. The purpose of this guideline is to help clinicians to diagnose correctly and treat efficiently patients with cough. In this article, we have stated recommendation and summary of...