نتایج جستجو برای: hadha
تعداد نتایج: 71 فیلتر نتایج به سال:
Previously we proposed a heparin/protamine-based system for delivery of protease drugs such as tissue-specific plasminogen activator (tPA). To demonstrate the feasibility of this approach as well as its pro-drug and triggered release features, positively charged peptides [(Arg)(7)Cys] were successfully linked to tissue-specific plasminogen activator (tPA) using the crosslinking agent N-succinim...
Conformations of the crystalline 3,3,3-trifluoro-2-methoxy-2-phenylpropanamide derivatives (MTPA amides) deposited in the Cambridge Structural Database (CSD) were examined statistically as Racid-enantiomers. The majority of dihedral angles (48/58, ca. 83%) of the amide carbonyl groups and the trifluoromethyl groups ranged from -30° to 0° with an average angle θ1 of -13°. The other conformationa...
The strict application of IUPAC rules for the numbering of tropane alkaloids is not always applied by authors and there is hence a lot of confusion in the literature. In most cases, the notation of 3, 6/7-disubstituted derivatives has been chosen arbitrarily, based on NMR and MS data, without taking into account the absolute configuration of these two carbons. This paper discusses the problem a...
the Biocidal Products Regulation adopted by the Council and Parliament in the spring entered into force on July 17, 2012. the regulatory requirements for industry will apply from September 1, 2013 and eCHA is preparing to start the new regulatory processes by that date. the new regulation sets rules for placing biocidal products on the market. the aim is to simplify and harmonize the procedures...
12-O-Tetradecanoylphorbol-13-acetate (TPA) is an ef fective comitogen in phytohemagglutinin-treated bovine lymphocytes. Concurrent addition of 10 8 MTPA gives a greater than 6-fold increase in DNA synthesis over cul tures treated with the lectin alone. The delayed addition of phorbol ester, relative to the start of the lectin treat ment, eliminates this synergistic action. Structure-func tion s...
High-energy diets improve growth rates and shorten the period while resulting in excessive fat deposition liver of birds. The effect different energy on lipid content transcriptome finisher Huxu chickens was examined here. A total 200 90-d-old with an average BW 1.08 kg were randomly divided into two dietary treatments. birds fed either containing 12.06 MJ ME/kg (low metabolic energy, LME) or 1...
Neoadjuvant chemoradiation (nCRT) is an established procedure in stage union internationale contre le cancer (UICC) II/III rectal carcinomas. Around 53% of the tumours present with good tumor regression after nCRT, and 8%-15% are complete responders. Reliable selection markers would allow the identification of poor or non-responders prior to therapy. Tumor biopsies were harvested from 20 patien...
In course of our screening for new secondary metabolites from ecological niche specialized, phytopathogenic fungi, the plant pathogen Elsinoё pyri, strain 2203C, was found to produce four novel compounds (1-4), which were named elsinopirins A-D, in addition to the known metabolite elsinochrome A (5). After isolation by preparative high-performance liquid chromatography (HPLC), their structures,...
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