نتایج جستجو برای: hba2
تعداد نتایج: 435 فیلتر نتایج به سال:
ABSTRACT: Iron deficiency anemia (IDA) in humans is defined as the decrease of total hemoglobin concentration and non-production adult subtype 2 - HbA2 (α2δ2 chains), which considered a marker IDA severity humans, dosed together with iron serum. This study aimed to determine standard types piglets induced experimentally first 21 days life (delivery weaning). In present study, 40 born from four ...
The Black Sea wave climate was the subject of various studies and research projects. In the last years this region becomes an important corridor for energy transportation. These new economical developments are leading to increased sea traffic and request the possibility of better prediction systems for the wave conditions especially concerning the nearshore areas in the neighborhood of the majo...
Hemoglobin (Hb) D. Punjab [β121(GH4) Glu→Gln; HBB: C.364G>C] and β0-thalassemia 3.4 kb deletion are very rare in the Thai population. For the first time, the coinheritance of HbD-Punjab with β0-thalassemia 3.4 kb deletion was reported in a 7-year-old Thai girl. She had mild anemia (Hb 115.0 g/L and mean corpuscular hemoglobin 18.1 pg) with red blood cell microcytosis (mean corpuscular volume 52...
Two Chinese patients with mild and moderate hemoglobin (Hb) H disease were investigated for rare mutations in the α-globin genes (HBA1, HBA2) in addition to --(SEA) deletion. One patient was a 41-year old man with mild anemia (Hb 11.3 g/dl). Multiplex ligation-dependent probe amplification (MLPA) revealed a rare 2392-base deletion involving the entire HBA1. Mapping by gap-polymerase chain react...
alpha Thalassemia modifies the hematologic expression of homozygous sickle cell (SS) disease, resulting in increased total hemoglobin and HbA2 and decreased HbF, mean cell volume, reticulocytes, irreversibly sickled cells, and bilirubin levels. The age at which these changes develop in children with SS disease is unknown. Ascertainment of globin gene status in a large representative sample of c...
BACKGROUND AND OBJECTIVES Beta-thalassemia continues to be a cause of significant burden to the society, particularly in the poorer developing countries. The objective of the present study was to evaluate the validity of "NESTROFT" (Naked Eye Single Tube Red Cell Osmotic Fragility Test) as a useful screening tool in the diagnosis of beta thalassemia trait. MATERIAL AND METHODS The present stu...
Haemolytic anaemia is variable among patients with sickle cell anaemia and can be estimated by reticulocyte count, lactate dehydrogenase, aspartate aminotransferase and bilirubin levels. Using principal component analysis of these measurements we computed a haemolytic score that we used as a subphenotype in a genome-wide association study. We identified in one cohort and replicated in two addit...
objective: this study was designed to investigate rbc indices and hba2 levels in parents of major beta-thalassemia patients to detect possible silent beta- thalassemia carriers and examine its potential impact on the premarital genetic counseling. materials and methods: this cross sectional study was performed at children medical center from 2004 to 2006. after genetic counseling and getting in...
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