The Assessment of Quality of Life (AQoL), developed by Australian researchers, is a multi-attribute utility (MAU) health-related quality of life instrument. While it can be used to measure health-related quality of life alone, its main purpose is to measure the ‘utility’ of health states (that is, the preferences people have for different health states) in a way suitable for use in economic eva...

INTRODUCTION Opioid-induced constipation (OIC) is the most common side effect of opioid treatment. Treatment for OIC typically involves a laxative. However, some patients have an inadequate response to these (laxative inadequate responders, or LIR). This has led to the development of treatments such as naloxegol. This analysis estimates the impact of naloxegol on the health state utility of LIR...

Health outcomes measurement forms a key aspect of data collection for economic evaluations. Quality-of-life instruments provide a measure of patient-focused health outcomes. Such instruments, including the EuroQoL questionnaire (EQ-5D) and the Short-form 36 (SF-36) are already being used in Japan. Utility instruments provide an alternative way of measuring quality of life for use in economic an...

BACKGROUND Chronic angina is a profoundly symptomatic disease. We evaluated the relationship between angina frequency and health utility. METHODS We used data from stable angina patients reporting ≥3 attacks/week enrolled in the Efficacy of Ranolazine in Chronic Angina (ERICA) trial. Angina frequency was classified using the Seattle Angina Questionnaire angina frequency (SAQAF) domain into no...