نتایج جستجو برای: heart injury

تعداد نتایج: 689224  

Journal: :Science 2012
Guo N Huang Jeffrey E Thatcher John McAnally Yongli Kong Xiaoxia Qi Wei Tan J Michael DiMaio James F Amatruda Robert D Gerard Joseph A Hill Rhonda Bassel-Duby Eric N Olson

The epicardium encapsulates the heart and functions as a source of multipotent progenitor cells and paracrine factors essential for cardiac development and repair. Injury of the adult heart results in reactivation of a developmental gene program in the epicardium, but the transcriptional basis of epicardial gene expression has not been delineated. We established a mouse embryonic heart organ cu...

Ali Khoshbaten, Ali Noroozzadeh, Bahram Rasoulian, Gholamreza Baqeri, Hamidreza Taghipour, Hassan Mohammadhosseniakbari, Hossein Eimani, Mahmood Mofid, Mahvash Jafari, Seid Mohammad Hassan Hashemimadani,

Introduction: Using brief episodes of ischemia and reperfusion (IR) prior to a more sustained IR insult – ischemic preconditioning (IPC) – can reduce IR injury of the heart, brain and many other tissues. The purpose of present study was to investigate the effect of 2min ischemic periods on subsequent rat renal IR injury. Methods: Male rat's renal IR injury was investigated in a right nephrectom...

Journal: :Brazilian Journal of Cardiovascular Surgery 2019

Journal: :Indian Journal of Pharmaceutical Sciences 2022

The present study was designed to investigate the role of estrogen receptor and KATP channel in cardioprotective effect remote aortic preconditioning rat heart. Remote is a phenomenon which brief episodes ischemia reperfusion organs protect target organ against sustained ischemia/ induced injury. Protective effects are well established heart, but their mechanisms still remain be elucidated. rat...

Journal: :Trauma Surgery & Acute Care Open 2019

2016
Fawzi A. Babiker

Ischemic heart disease, also known as coronary heart disease or coronary artery disease, accounts for >50% of cardiovascular events and is a leading cause worldwide of morbidity and mortality. Hypoperfusion of the heart is the major cause of injury in ischemic heart disease, as it results in the death of cardiomyoctes due to a lack of oxygen and energy. This injury ultimately leads to a dead ar...

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