In the framework of cardiac electrophysiology for human heart, we apply multipatch NURBS-based Isogeometric Analysis space discretization Monodomain model. (IGA) is a technique solution Partial Differential Equations (PDEs) that facilitates encapsulating exact representation computational geometry by using basis functions with high-order continuity. IGA features very small numerical dissipation...

1. Abstract 2. Introduction 3. Materials and Methods 3.1. Animals 3.2. Experimental procedures 3.3. Immunohistochemistry 4. Results 4.1. Adult rat 4.1.1. Transferrin receptor 4.1.2. Transferrin 4.1.3. OX26 4.1.4. Non-immune IgG 4.2. P7 rat 4.2.1. Transferrin receptor 4.2.2. Transferrin 4.2.3. OX26 4.2.4. Non-immune IgG 5. Discussion 5.1. Circulation of transferrin and OX26 in the brain 5.2. Cel...

The aim of the present study was to examine the effect of cardiac anisotropy on the ECG inverse localization solutions using a heart-model-based approach. The anisotropic heart model was used in forward pacing simulation while anisotropic and isotropic heart models were used in inverse procedures, respectively. Twenty-four sites throughout the ventricles were paced and the sites of origins of v...

This study introduced a combined computational fluid dynamics (CFD) and echocardiography methodology to simulate blood flow in the single right ventricle (SRV) and normal ventricles to study the intraventricular flow. Derived from echocardiographic image loops, CFD-based three-dimensional (3D) flow models of normal subject's left ventricle (LV) and right ventricle (RV) and SRV with and without ...

The conduction disturbances in atrioventricular block are well known from numerous electro-cardiographic studies, but the effect on the heart work, especially on the individual chambers, could not be recorded before the introduction of visualization of the heart chambers by angio-cardiography. Rapid biplane angiocardiography with simultaneous electrocardiographic yields information on cardiac d...

Based on the sequentiality principle, this review proposes a practical method that allows the systematization of the anatomic diagnosis of congenital heart disease. We emphasize the need to use sequential connection between the different cardiac segments: atria, ventricles and great arteries. Five ordered steps are defined, which include determination of atrial situs and of the connection featu...