background: autophagy suppression recently has been known to have a remarkable effect for cellular adjustment and viability in the final stages of cancer. on the other hand, autophagy has the potential effect in preventing many viruses from replication. beclin1 is the most substantial constituent in autophagy apparatus regulation. this study was intended to investigate the beclin1 sirna knockdo...

three differentes continous cell lines (am 57. hela • vero) and primary cell culture of human embryo kidney are compared with regard to their .susceptibility for isolation of mumps v i r u s from saliva and cerebrospinal fluid. for this purfose the vero cell line appeared to be more suitable among the studied cell systems regarding the following reasons: it allows the highest pourcentage of mum...

objective: lactobacilli are a group of probiotics with beneficial effects on prevention of cancer. however, there is scant data in relation with the impacts of probiotics in late-stage cancer progration, especially metastasis. the present original work was aimed to evaluate the anti-metastatic and anti-proliferative activity of lactobacillus rhamnosus supernatant (lrs) and lactobacillus crispat...

toxoplasmosis is a protozoal infection caused by toxoplasma gondii. toxoplasmosis produce severe damage in patients who are immunosuppresed. in those who are immunosupressed, latent infection can be reactivated resulting in acute disseminating disease. betamethasone is a synthetic glycocorticoid, used as an anti-inflamatory and immunosuppressant in a wide variety of disorders.the aim of this st...

There have been efforts to overcome the problem in treatment of cancer using medicinal plants. It has been shown that Citrus essential oil of contains different terpens with antitumor activities. In this study we sought to determine the cytotoxicity of essential oils of Iranian Citrus limon (L.), C. medica (L.), C. sinsensis (L.) peels on cancer cell lines. Essential oils were prepared by hydr...

The HeLa cell line is the oldest, most widely distributed, permanent human cell line. As a nearly ubiquitous inhabitant of laboratories using tissue culture techniques, its aggressive growth characteristics make it a problematic contaminant that can overgrow less robust cell lines. Consequently, HeLa contamination is common in both the research laboratory and cell line repository contexts, and ...

introduction: the aim of this study was to determine a proper cell line for adherance of helicobacter pylori and a suitable method for attachment of this bacteria to cell lines in vitro. material and methods: a total of 22 h.pylori strains,isolated from the antral biopsies of 49 patients with dyspepsia,gastritis,gastric ulcer,duodenal ulcer, etc., were evaluated by elisa(upr)to determine the di...

Two set of 2-aryl-5,6-dihydropyrrolo[2,1-a] isoquinolines were designed and synthesized to evaluate their biological activities as topoisomerase inhibitors. Cytotoxic activity of the synthesized compounds 4a-e and 7a-d was assessed against several human cancer cell lines, including MCF-7 (breast cancer cell), HepG2 (liver hepatocellular cells), A549 (adenocarcinomic human alveolar basal epithel...

Two set of 2-aryl-5,6-dihydropyrrolo[2,1-a] isoquinolines were designed and synthesized to evaluate their biological activities as topoisomerase inhibitors. Cytotoxic activity of the synthesized compounds 4a-e and 7a-d was assessed against several human cancer cell lines, including MCF-7 (breast cancer cell), HepG2 (liver hepatocellular cells), A549 (adenocarcinomic human alveolar basal epithel...