Large-scale genome-wide association results are typically obtained from a fixed-effects meta-analysis of GWAS summary statistics from multiple studies spanning different regions and/or time periods. This approach averages the estimated effects of genetic variants across studies. In case genetic effects are heterogeneous across studies, the statistical power of a GWAS and the predictive accuracy...

The Antoine equation is a semi-empirical equation which expresses vapour pressure as a function of temperature. A new, rapid and highly accurate method for obtaining its three constants from experimental data is presented and applied to ethanol, water and 14 anaesthetic substances. Alternative vapour pressure equations are discussed and references for original temperature--vapour pressure data ...

Over recent years, spreadsheets have been increasingly recognised as having a role in teaching and learning mathematics, but have continued to suffer the limitation of requiring access to computers. This paper summarises some of the potential benefits of spreadsheet use and briefly assesses some of the available research about it in schools. A spreadsheet application for a calculator is describ...

This paper presents a new MATLAB interface calculator based on the transmission line theory approach to design a parallel coupled microstrip band pass filters (PCMBPF). All formulas of the PCMBPF are programmed using the closed-form mathematic expressions and the coupling matrix concept. The proposed new interface calculator allows scientist and engineers to obtain the whole parameters required...

The development of an estimator for vapor pressure based upon organic functional groups is described. This vapor pressure calculator permits prediction of vapor pressure for a wide range of structural classes. The statistical quality of the derived coefficients is presented as well as the quality of the prediction of the training set of compounds. The calculator is then used to predict the vapo...

The study of information as proposed in information theory provides a useful tool for studying many aspects of information systems, libraries, and archives. How does a calculator that computes information-theoretic functions contribute to students learning database ideas such as the relationships between various attributes, or columns in a relational database? Understanding the relationships be...

In this paper a geometric calculator is presented. A language of geometrical expressions, that are evaluated by the calculator, and the design and implementation of its interpreter is also presented. Geometrical expressions correspond to abstract data-types that can be defined dynamically through composition operations. Diagrams can be represented by a set of geometrical expressions, and the ge...

Abstract – In last decades, diversity and accuracy have been regarded as two essential measures in evaluating recommender systems. However, a clear concern is that a model focusing excessively on one measure will put the other one at risk, which means that it is not easy to greatly improve diversity and accuracy simultaneously. In this paper, we propose a method which can be used in many being ...