Collagen vascular diseases (CVDs) like systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren syndrome (SS), and scleroderma are immunologically mediated disorders that typically have multisystem involvement. Although clinically significant liver involvement is rare, liver enzyme abnormalities are common in these patients. The reported prevalence of hepatic involvement in SLE, histop...

A variety of hepatic manifestations may occur during attacks of acute amoebic dysentery, conforming to clearly defined clinical groups. The incidence of definite hepatic involvement presenting as cases of hepatic amoebiasis with or without demonstrable pus or with tender hepatomegaly was 57-5%. While it is possible that the cases presenting with hepatic manifestations without demonstrable pus a...

Systemic mastocytosis is a myeloproliferative disorder characterized by extracutaneous involvement of at least one organ. Although rare, infiltration of inflammatory mast cells within the portal vein may lead to obstruction of the sinusoids resulting in non-cirrhotic portal hypertension. We present a patient with known history of systemic mastocytosis with bone marrow involvement presenting wit...

Parent involvement (PI) in school is associated with more positive academic performance and social competence in children. However, there are inadequacies in current measures of PI and a need for a better understanding of predictors of PI. In this study, measures were obtained from a normative sample of 387 children in kindergarten and first grade from high-risk neighborhoods in 4 different sit...

Hereditary hemorrhagic telangiectasia (HHT), or Osler-Rendu-Weber syndrome, is a heterogeneous inherited disorder characterized by multi-systemic vascular dysplasia and wide variation in its phenotypic expression. Hepatic manifestation is seen in about 8 to 30 % of the patients. The molecular basis for liver involvement is unknown. We screened the two known HHT disease loci, the ALK1 (ACVRL1) a...

Histologic examination of liver tissue obtained by needle biopsy has vastly improved knowledge of hepatic diseases and of systemic diseases with hepatic involvement. In addition, liver biopsy has become a valuable tool in solving difficult clinical diagnostic problems. Diagnosis of tuberculosis has been established by means of liver biopsy on numerous occasions.’4 The extent of hepatic involvem...

Through the use of antibodies produced against homogeneous bovine adrenal ferredoxin, the presence of hepatic ferredoxin in rat hepatic mitochondria, its immunochemical similarity to adrenal ferredoxin, and its involvement in the hepatic mitochondrial cholesterol hydroxylase and NADPH-cytochrome c reductase activities have been demonstrated. Employing rabbit antiserum to bovine adrenal ferredox...

BACKGROUND Hydatidosis is one of the major zoonotic diseases that cause considerable public health problems in Iran. The present study was designed to investigate pediatric hydatidosis in patients referred to the Children Medical Center Hospital in Tehran, Iran during 2005-2010. METHODS Data were collected from the records of 17 patients referred to the center with hydatidosis. Data included ...

The objective of this investigation was to study the gastrointestinal and hepatic involvement in hypereosinophilic syndrome (HES). Gastrointestinal or hepatic involvement is estimated to affect up to one-third of patients with HES, although most of the clinical evidence has been derived from case reports. In literature, HES presenting with hepatitis and jaundice with subsequent development of c...