The hepatitis B prevalence rate in adults is still at a high to intermediate level in China. Our purpose was to explore the incidence rate and protective immune barrier against hepatitis B in adults in China. A sample of 317961 participants was multi-screened for hepatitis B surface antigens (HBsAg) in a large-scale cohort of the National Hepatitis B Demonstration Project. A total of 5401 perso...

Abstract Background and Aims Patients with end-stage renal disease (ESRD) frequently present serologic evidence of previous contact hepatitis B virus (HBV). Although uncommon, HBV reactivation after kidney transplantation (KT) may cause serious complications adverse outcomes in these patients. However, data regarding risk factors for are still scarce. This study aims to describe a cohort patien...

BACKGROUND Health care workers are at high risk of acquiring hepatitis B virus (HBV) infection through occupational exposure to blood or body fluids. Thus, the assessment of anti-HBs status after immunization is very important. OBJECTIVES This study aimed to evaluate the measurement of HBsAb titer and specific gamma interferon response among the vaccinated health care workers in Golestan Hosp...

HYPOTHESIS Hepatic allografts from donors positive for antibody to hepatitis B core antigen (anti-HBc) frequently transmit hepatitis B virus (HBV) infection to recipients. Therefore, most transplantation centers will not use these organs for orthotopic liver transplantation (OLT). Although it is expensive and not always efficacious, hepatitis B immune globulin (HBIG) has been used routinely for...

BACKGROUND Some reports have documented the coexistence of Hepatitis B surfage Antigen (HBsAg) and anti-HBsAg antibodies (HBsAb) in patients with chronic hepatitis B (CHB), often in the absence of amino acid substitutions in the HBsAg sequences of the Hepatitis B Virus (HBV) genome able to explain an immunological escape variant.HBV genome has a very compact coding organization, with four parti...

results before boosting, among 176 boosted individuals, 75 (42.6%) had hbsab 10 iu/l and were considered seroprotected. among 101 serosusceptible persons, more than 80% of boosted individuals showed more than twofold increase in cytokines concentration, which meant positive hbsag-specific cell-mediated immunity. mcl of both cytokines after boosting in giv were decreased more than twofold, possi...

introduction: hepatitis b is a disease caused by the hepatitis b virus (hbv), which is transmitted through percutaneous (i.e., puncture through the skin) or mucosal (i.e., direct contact with mucous membranes) exposure to infectious blood or body fluids. hbv can cause chronic infection, resulting in cirrhosis of the liver, liver cancer, liver failure, and death. persons with chronic infection a...

BACKGROUND Human immunodeficiency virus (HIV) infected patients are also frequently exposed to the hepatitis B virus (HBV), due to the common routes of transmission, therefore, prevention of hepatitis B results in decreased complications of the disease. OBJECTIVES Since the immune response of HIV patients to hepatitis B vaccination is less robust than that found in healthy individuals, this s...

conclusions being a barber alone is not a potential risk factor for hbv infection, while hcv infection is still an occupational health hazards for barbers. we suggest more extensive case-control studies with regard to rates of hepatitis b and c markers among barbers in other iranian cities to assess the incidence of hepatitis b and c infections among this population. background hepatitis b viru...