نتایج جستجو برای: hepatotoxic effect
تعداد نتایج: 1642793 فیلتر نتایج به سال:
we studied the hepatotoxic effects of a deltamethrin containing formulation (decis®) on developing em-bryo of gallus domesticus. fertilized eggs were immersed in three different concentrations of deltamethrin (12.5, 25 and 50 mg/l) for 60 min at 37 ˚c prior to incubation (ed 0) and on the 4th day of incubation (ed 4) and incubated till embryonic day (ed) 16. exposure to 50 mg/l of deltamethrin ...
Extracts from Boswellia serrata have been reported to have anti-inflammatory activity, primarily via boswellic acid-mediated inhibition of leukotriene synthesis. In three small clinical trials, boswellia was shown to improve symptoms of ulcerative colitis and Crohn's disease, and because of its alleged safety, boswellia was considered superior over mesalazine in terms of a benefit-risk evaluati...
Microcystin-FR a cyclic heptapeptide was isolated from Nostoc spongiaeforme and purified by thin layer chromatography, MALDI TOFF Ms and HPLC methods. The Swiss albino mice dosed with the sub lethal concentration of 0.8μg/kg body weight of microcystin-FR were subjected to a battery of behavioural depression models such as tail suspension test (TST), force swim test (FST) and elevated plus maze ...
We report herein the straightforward two-step synthesis and biological assessment of novel racemic benzochromenopyrimidinones as non-hepatotoxic, acetylcholinesterase inhibitors with antioxidative properties. Among them, compound 3Bb displayed a mixed-type inhibition of human acetylcholinesterase (IC50 = 1.28 ± 0.03 μM), good antioxidant activity, and also proved to be non-hepatotoxic on human ...
Although one member of the H2 blocker family (oxmetidine) proved to be intrinsically hepatotoxic, overt hepatic injury attributable to cimetidine and ranitidine is decidedly rare, given the tens of millions of patients who have received these medications. Even considering the fact that serious adverse reactions may be underreported by as much as a factor of 100, the number of reports submitted ...
BACKGROUND Large proportions of patients use herbal medicinal products, and encouraging data in terms of effectiveness exist for some of these. One aspect, however, which is still largely under-investigated is the question of potential harm. AIM To review the recent evidence on hepatotoxic events associated with the use of herbal medicinal products. METHODS Systematic literature searches we...
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